Correlation of the Clinical Diagnosis of Cutaneous Leshmaniasis with Skin SLT Smear Histology and Culture at Dermatology Clinic, ALERT Center from May 2018 to May 2020 G.C Addis Ababa, Ethiopia.
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Date
2021-09
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Addis Abeba University
Abstract
Background: Leishmaniasis is a complex of diseases caused by the protozoa Leishmania and
transmitted by the bite of infected phlebotomine sandfies.
clinical diagnosis of CL may be possible in endemic areas.since the treatment is potentially toxic
laboratory confirmation is mandatory.
Objective:To asses correlation of clinical diagnosis of cutaneous leishmaniasis with positive
laboratory tests used for the identification of leishmania parasite (skin slit smear ,culture and
histopathology)among clinically diagnosed cases at dermatology clinic ,ALERT center from May
2018 to May 2020 G.C Addis Ababa, Ethiopia.
Methodology: retrospective review of medical records of patients diagnosed with cutaneous
leishmanias in ALERT Hospital, AA, Ethiopia from May 2018 to May 2020 was performed .
Patient medical records retrieved and analyzed using SPSS Version 24.
The results will be submitted to ALERT hospital, AAU College of Health Sciences, Department of
Dermatovenerology, School of Public Health and FMOH.
Results: Total of 215 were clinically diagnosed as cutaneous leishmaniasis by the dermatologist
and dermatology residents.
Out of 215, 158 (73.5%) patients were slit-skin-smear (SSS) positive,culture was done for 57
patents ,25 /215(11.6%) and histopathology done for 32/215(14.9% ), from these LD body seen in
4/32(12.5%) and in 25/32(78.13%) suggestive histology result and in 3/32(9.34%) diagnosis of
other diseases was made.
Conclusion: In our study , slit-skin-smear (SSS) positivity was 73%(158/215), culture positivity
was 43.84%(25/57) and histopathology positivity was 90.6% (29/32).
From total of 215 clinically suspected case 208 cases was diagnosed with one of the investigation
modality SSS,culture or histopathology.Therefore clinical suspected cases by the clinician became
96.7% (208/215) positive.
Recommendation: In limited resources setting and clinical accuracy of 96.7 %, clinical diagnosis
by a dermatologist showed significantly comparable positive result with the laboratory
investigation
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Keywords
Leishmaniasis