Histopathologic Patterns of Neoplastic and Non-neoplastic Kidney Lesions in Nephretcomy Specimen in Tikur Anbesa Specialized Hospital, Addis Abeba, Ethiopia, Over a Five Year Period, 2017-2021
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Date
2022-01
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Addis Ababa University
Abstract
Background : The kidney is one of the major organs that have essential functions such as maintaining electrolyte balance and ph as well removing waste products among other things. Various neoplastic and non-neoplastic lesions affect the kidneys for which nephrectomy are the standard procedure performed. The indications, however, differ by geographic location , age groups and time periods .Therefore ,the aim of this study is to determine the patterns of neoplastic and non neoplastic lesions in nephrectomy specimens in TASH.
Methods and Materials This was a retrospective cross sectional descriptive study conducted on 174 patients having Histopathologic evaluation of their nephrectomy specimens at Tikur Anbesa Specialized Hospital from September 2017 and August 2021.
Result : 92 (52.9%) of the study subjects were females while remaining 82(47.1%) were male with male to female ratio of 0.9;1 . Neoplastic diseases accounted for 75.2 percent, nonneoplastic 22.4 and multicystic renal dysplasia 2.3 percent . The mean age of patients was 31.95 with SD 22.127 with minimum and maximum age of 6 month and 75 years respectively. The most common neoplatsic indication for nephrectomy was renal cell carcinoma [N=69] constituting 39.7 percent followed by nephroblastoma 26.4 percent [N=46]. The most common non-neoplastic lesion was CPN with HN accounting for 35.5 percent.
Conclusion : A wide Histopathologic spectrum of neoplastic and non neoplastic diseases were found in the present study. There is a decline in non-neoplastic lesions which may be due to early diagnosis and treatment.
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Non-Neoplastic lesions, Neoplastic lesions, nephrectomy