Trend and Determinants of Treatment outcome of Severe Malaria among under-five Children Admitted in Karat Primary Hospital, Konso Zone, Southwest Ethiopia, 2021: Retrospective Cross-sectional study
No Thumbnail Available
Date
2021-10
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Addis Abeba University
Abstract
Background: Despite rigorous global and national efforts, malaria remains a significant cause of morbidity and mortality among under-five children. It causes a serious healthand economic burden globally, in sub-Saharan countries including Ethiopia in particular.In 2019, children alone contribute 67% of the global malaria mortality burden. Fewstudies were conducted to determine the trend, treatment outcome of severe malaria andits determinants among under-five children in Ethiopia.
Objectives: The main aim of this study was to assess trend and determinants of treatmentoutcome of severe malaria among under-five children in karat primary hospital, konsozone, Southwest Ethiopia, 2021.
Methods: An institution based retrospective cross-sectional study was conducted.Consecutive sampling was applied for the trend analysis of five-year malaria incidencefrom Feb 08-Mar 08 2021. 254 charts were selected by systematic random samplingtechnique from June10-30,2021. Data was collected by trained data collectors using apre-tested checklist. The collected data was cleaned and entered using Epi-data 4.6 andanalyzed using SPSS version 25. Descriptive statistics was used to summarize the studyvariables. Bivariate and multivariable logistic regressions was used to determine theassociation between determinants and outcome variable. Odds ratio with 95% CI wasused to show the direction and strength of association. P-value <0.05 was used to declarestatistical significance.
Result: From a total of 7663 malaria suspects, 2572 was confirmed positive making overall positivity of 33.5%. Plasmodium falciparum attributed for 1904(74%) of confirmedcases. Fluctuating up and down trend with seasonal variation with highest cases wasobserved in autumn and the lowest in winter of the all years. Among 254 childrenadmitted with severe malaria 37(14.6%) was died. Children in age group of 48-59months AOR =0.04 (95% CI 0.00-0.87), government employed mothers AOR=0.19(95% CI 0.04-0.92), co-morbidity AOR=14.08 (95% CI 3.04-65.27), prolonged hospitalstay AOR=10.31(2.55-41.67) and late treatment seeking AOR=6.37 (95% CI,1.67- 25)were more likely to die.
Conclusion: Malaria remained the common public health challenge in the study areawith no significant reduction during the five-year period. The mortality due to severmalaria was also high with various factors such as age of the child, maternalemployment, co-morbidity, prolonged hospital stays and late treatment seeking wassome of the factors that increased the odds of death. Therefore, intensification of keyintervention activities should be implemented with the focus on the identified riskfactors.
Description
Keywords
Severe malaria, Treatment outcome, Under-five children, Trend, Konso, Ethiopia