The Prevalence of Hepatitis B Virus Infection and Associated Factors Among Hiv Positive Adults Attending Art Clinic at Selected Public Hospitals, Addis Ababa, Ethiopia
| dc.contributor.advisor | Abebe, Mesfin (PhD) | |
| dc.contributor.author | Biru, Mulushewa | |
| dc.date.accessioned | 2018-07-17T05:54:56Z | |
| dc.date.accessioned | 2023-11-06T09:01:51Z | |
| dc.date.available | 2018-07-17T05:54:56Z | |
| dc.date.available | 2023-11-06T09:01:51Z | |
| dc.date.issued | 2017-06 | |
| dc.description.abstract | Back ground- Liver disease is the single greatest cause of non AIDS related death in patients with HIV disease, accounting for a greater proportion of deaths than non AIDS related cancers. Most liver disease among HIV-infected individuals is secondary to confection with HBV. Many HIV positives might be co-infected with HBV. It might result in cancer, cirrhosis, liver failure and death. Objective: The aim of this study was to determine prevalence of Hepatitis B Virus Infection and Associated Factors among HIV Positive Adults Attending ART Clinic at Tikur anbessa specialized referral, Zewditu and Alert hospitals, Addis Ababa, Ethiopia March-April, 2017. Methods: An institution based cross-sectional study was conducted on outpatients at ART clinic from TASH, Zewditu Memorial hospital, and Alert hospital from March-April, 2017. A sample size of 169 participants was selected by using systematic random sampling method. Data was collected using pre-tested interviewer administered structured questionnaires and by reviewing charts for HBsAg that was routinely screened with laboratory technicians of the hospitals. Frequencies distribution, bivariate and multivariate logistic regressions were done. P <0.05 with 95% CI was considered statistically significant. Results: From 169 HIV positive adults’, 165 of them were included in the analysis with a response rate of 97.6%.Majority of the study participants 99(60.0%) were female and the mean age of the participants was 38.9 9.89 SD years. The prevalence of HBsAg was found to be 12 (7.3%); of whom 3(25%) were females and 9 (75%) were males and multivariate analysis revealed that those who was male 5.7 times more likely contaminated with HBV coinfection than female [AOR 5.726; 95% CI 1.346-24.362]. Those who have previous history of Dental extraction were 6.4 times more likely to be contaminated with HBV than who did not [AOR = 6.4: 95% CI, 1.256-33.097]. Conclusion: the prevalence of HBV infection was found to be intermediate in HIV infected patients in the study area. Regarding Sex distribution, males were frequently infected with HBV than females. Furthermore, in this study it was also observed a greater HBV Prevalence among individuals having a history of multiple sexual practices; opportunistic infection and dental extraction were found statistically associated factors for HBV infection. Keywords: HIV/AIDS; HBV; Adult patients; Co-morbidity; Associated factors | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/8824 | |
| dc.language.iso | en | en_US |
| dc.publisher | Addis Ababa University | en_US |
| dc.subject | Public Hospitals | en_US |
| dc.subject | Hepatitis B virus | en_US |
| dc.title | The Prevalence of Hepatitis B Virus Infection and Associated Factors Among Hiv Positive Adults Attending Art Clinic at Selected Public Hospitals, Addis Ababa, Ethiopia | en_US |
| dc.type | Thesis | en_US |