Cytopathologic Patterns of Thyroid Lesions and Correlation of FNAC Reports with the Corresponding Bstopathologic Results at a Tertiary Hospital in Ethiopia, a five-year Retrospective Study Between January 2015 and August 2019.
| dc.contributor.advisor | Dr.Gemechu, Tufa(MD, Associate professor of pathology) | |
| dc.contributor.author | Jember, Woldie | |
| dc.date.accessioned | 2020-06-18T19:31:14Z | |
| dc.date.accessioned | 2023-11-05T09:34:31Z | |
| dc.date.available | 2020-06-18T19:31:14Z | |
| dc.date.available | 2023-11-05T09:34:31Z | |
| dc.date.issued | 2019-06 | |
| dc.description.abstract | Background Thyroid diseases are among the most common endocrine disorders worldwide including in Ethiopia and Patients with thyroid diseases can present with diffuse or nodular thyroid enlargement. Determining the type of the lesions in a given setup has paramount importance to design effective therapeutic strategy. As a result, the aim of this study was to find out the cytological patterns of thyroid lesions and compare these cytopathologic reports with their corresponding histopathologic diagnosis at Black Lion Hospital. Methods This was a retrospective cross sectional descriptive study conducted on 687 patients having cytopathologic evaluation for thyroid lesions at Black Lion Hospital between January 2015 and August 2019. Results: Most of the patients were in the age range of 20-60 years, accounting for 521/663(77.3%) cases with Mean age of 41.98 and F:M ratio of 4.69:1. Non- diagnostic(Inconclusive), Benign (Non-neoplastic lesions), Follicular neoplasm, Hurthle Cell neoplasm, Suspicious for malignancy and malignant cytopathologic diagnosis accounted for 33(4.8%), 504(73.4%), 51 (7.4%), 11(1.6%),3(0.4%) and 85(12.4%) of the cases respectively. Among the Benign (Non-neoplastic lesions), Colloid Goitre was the most common diagnosis occurring in 458(90.9%) of the cases. The minimum and maximum age for the occurrence of malignancy in the study was 21 and 80 years old respectively and Papillary Carcinoma was the leading type of malignancy accounting 43(48.9%) of all malignant cases followed by Anaplastic(Undifferentiated) Carcinoma constituted 20(23.6%) of the malignant vi cases. From all 687 patients with cytopathologic evaluation, only for 19 of them were histopathologic reports available for comparison. Eleven of the 19 cases were diagnosed benign(non-neoplastic) lesions by FNAC and 2 ended up with malignant diagnosis histologically. Six of the 19 cases had malignant diagnosis by FNAC and 2 became adenoma up on histologic examination. Conclusion: FNAC is an important tool for the management of thyroid lesions. It is simple, cost-effective technique without any major complications and with minimal discomfort to the patient. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/21805 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Ababa University | en_US |
| dc.subject | FNAC, Thyroid lesions, Non-Neoplastic lesions, Neoplasms | en_US |
| dc.title | Cytopathologic Patterns of Thyroid Lesions and Correlation of FNAC Reports with the Corresponding Bstopathologic Results at a Tertiary Hospital in Ethiopia, a five-year Retrospective Study Between January 2015 and August 2019. | en_US |
| dc.type | Thesis | en_US |