Phytochemical Investigation on the Seeds of Brucea antidysenterica
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Date
2005-07
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Addis Ababa Universty
Abstract
Brucea antidysenterica J. F. Mill. (Simaroubaceae) is a well known shrub from
the bark of the plant many quassinoids including the antileukemic compounds bruceantin,
which was in phase II clinical trial by the National Cancer Institute (USA).
In this work it was possible to isolate four compounds from the seeds: two glycosidic
quassinoids (BA5 and BA6), one alkaloid (BA2) and one flavonoid (BA7B). Their
structures were determined by spectral measurements and comparison with the previous
work.
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Brucea antidysenterica