Phytochemical Investigation on the Seeds of Brucea antidysenterica

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Date

2005-07

Authors

Tadesse Haregewine

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Addis Ababa Universty

Abstract

Brucea antidysenterica J. F. Mill. (Simaroubaceae) is a well known shrub from the bark of the plant many quassinoids including the antileukemic compounds bruceantin, which was in phase II clinical trial by the National Cancer Institute (USA). In this work it was possible to isolate four compounds from the seeds: two glycosidic quassinoids (BA5 and BA6), one alkaloid (BA2) and one flavonoid (BA7B). Their structures were determined by spectral measurements and comparison with the previous work.

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Brucea antidysenterica

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