Evaluation of Lipid Profiles and Hematological Parameters in Hypertensive Patients: A Cross Sectional Study at Debre Markos Referral Hospital, North West Ethiopia
No Thumbnail Available
Date
2017-03
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Addis Ababa University
Abstract
Introduction: Hypertension and dyslipidemia are the two coexisting and synergizing major risk
factors for cardiovascular diseases. The cellular constituents of blood affect the volume and
viscosity of blood, thus playing a key role in regulating blood pressure. Overweight and obesity
are key determinants of adverse metabolic changes including increase in blood pressure.
Objective: The aim of the present study was to evaluate lipid profiles and hematological
parameters in hypertensive patients at Debre Markos Referral Hospital, North West Ethiopia.
Materials and methods: Hospital based cross-sectional study was conducted in 100 hypertensive
patients at Debre Markos Referral Hospital. The required amount of blood was withdrawn from
the patients by health care professionals in the hospital for the immediate automated laboratory
analysis of the blood sample. Data were collected on sociodemographic factors, anthropometric
measurements, blood pressure, lipid profiles and hematological parameters.
Result: The mean serum levels of Triglyceride (TG), Total Cholesterol (TC) and Low Density
Lipoprotein (LDL) were significantly higher than their respective cut-off values in the hypertensive
patients. 54%, 52%, 35%, 11% of the hypertensive patients had abnormal LDL, TC, TG and High
Density Lipoprotein (HDL) levels respectively. Higher levels (p<0.05) of LDL, hemoglobin and
Red Blood Cell (RBC) count were observed in the hypertensive patients whose blood pressure had
been poorly controlled than the controlled ones. Waist circumference had significant positive
association with the serum levels of TC and White Blood Cell (WBC) count (p<0.05).
Conclusion: The hypertensive patients in this study had high prevalence of lipid profile
abnormalities and poorly controlled blood pressure which synergize in accelerating other
cardiovascular diseases. Some hematological parameters like RBC count are also increased as do
the severity of hypertension.
Key words: Hypertension, Lipid profiles, Hematological parameters, Anthropometric indicators
Description
Keywords
Hypertension; Lipid profiles; Hematological parameters; Anthropometric indicators