Assessment of Antidiabetic Medication Adherence and Its Effect on Glycemic Control in Ambulatory Patients with Type 2 Diabetes at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia
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Date
2014-12
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Addis Ababa University
Abstract
Poor adherence to treatment of chronic diseases is a worldwide problem of striking
magnitude. Adherence to long-term therapy for chronic illnesses in developed countries
averages 50%. In developing countries, the rates are even lower given the paucity of
health resources and inequities in access to health care. Poor adherence to recognized
standards of diabetes care is the principal cause of development of complications of
diabetes and their associated individual, societal and economic costs. Information on
adherence to antidiabetic medications and glycemic control among Type 2 diabetes
patients in Ethiopia is scanty. This study therefore sought to assess antidiabetic
medication adherence and glycemic control among 322 ambulatory patients with Type 2
diabetes mellitus attending at the diabetic clinic of Tikur Anbessa Specialized Hospital
(TASH). The study was a two phase, cross-sectional study conducted between 1 May-30
June 2014. Assessment of adherence was performed based on patients’ response to the
validated four-item Morisky instrument and the most recent fasting blood sugar level was
used for glycemic control. Adherence rate to antidiabetic medications was found to be
66.8%. Younger age, increased number of prescribed medications and job type (being a
farmer/daily laborer) were significantly associated with antidiabetic medication noniv
adherence. Most of the patients missed their medications because of forgetfulness. On the
other hand, only 12.7% of patients attained adequate glycemic control. Male sex, younger
age, low educational status, regular alcohol intake, exercise and dietary non-adherence
were observed to be significantly associated with poor glycemic control. Antidiabetic
medication adherence appeared to be positively associated with glycemic control (COR=
1.23, 95% CI: 0.6-2.5). Taken together, the findings indicated that adherence to
antidiabetic drugs was suboptimal and glycemic control was poor, which warrants the
need for health care providers engaged in diabetic care to aggressively address the issue.
Key words: Antidiabetic Medications, Adherence, Type 2 Diabetes, Glycemic control,
Fasting Blood Glucose
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Keywords
Antidiabetic Medications, Adherence, Type 2 Diabetes, Glycemic control, Fasting Blood Glucose