Screening of Parameters of Metabolic Syndrome and C-Reactive Protein (CRP) in Cigarette Smokers in Adama, Ethiopia

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Date

2014-01

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Addis Ababa University

Abstract

Background – Several previous studies indicated conflicting findings on parameters of Metabolic Syndrome and CRP in cigarette smokers. The aim of this study was to determine whether there is difference in levels of parameters of Metabolic Syndrome and CRP in cigarette smokers and non- smokers in Adama, Ethiopia. Methods – subjects were 99 healthy male individuals from age 15 to 60 years. The subjects were divided into two groups of 50 smokers and 49 non- smokers. BMI, blood pressure plasma levels of total cholesterol, triglycerides, HDL, and CRP were measured and LDL cholesterol was estimated using the Friedewald formula. Results – Overall subjects’ plasma levels of total cholesterol, triglyceride, LDL, HDL and serum CRP were significantly elevated in smokers. No significant difference was found in BMI, systolic and diastolic blood pressure between cigarette smokers and non-smokers. In smokers alcohol drinking was significantly correlated with increased plasma HDL, systolic and diastolic blood pressure while khat chewing was correlated with increased plasma total cholesterol. Conclusions – The results showed no difference in BMI between smokers and non smokers and also there was no significant difference in blood pressure in smokers and non smokers. Cigarette smoking is correlated with increased total cholesterol, TG, LDL, HDL and CRP. Among smokers blood pressure, total cholesterol and HDL were significantly higher in those whose alcohol consumption was higher.

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Keywords

Metabolic Syndrome; C-Reactive Protein

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