Polymer Translocation through Nanochannel :- a two Dimensional Monte Carlo Simulation Study
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Date
2013-06
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Addis Ababa University
Abstract
In this paper we investigate Monte Carlo(MC) simulation of polymer translocation through
a nanochannel. To this end we used the Bond Fluctuation Method (BFM) to study the
translocation process of a polymer chain of length N in two dimensions, in the absence
of external force on the polymer (i.e. unbiased translocation). To overcome the entropic
barrier we consider a polymer, in which the center monomer is initially placed in the
middle of the channel and study the escape time needed for the polymer to completely
exit the channel on either side of the end. Numerically we nd that the escape time
scales with the chain length N as N1+2 , where is the Flory exponent as far as the
channel is small enough. And this scaling preferably agree with the translocation time
of a polymer which passes through a nanopore in one direction only. In this work, we
examine the interplay between the channel length L, width W and other parameters while
simulating the translocation process
Keywords: Nanochannel, Translocation time, Escape time, DNA sequencing
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Keywords: Nanochannel, Translocation time, Escape time, DNA sequencing