Chemical Investigation of a Red Sea Sponge of the Genus Dysidea
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Date
1988-06
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Addis Ababa Universty
Abstract
A new hexachlorinated metabolite, for which the
'name dysidimide is proposed, has been isolated from a
Red Sea sponge of the genus Dysidea.
Dysidimide was the major metabolite obtained from
the ethanol extract o>f the dried sponge collected near
Massawa, Repeated column chromatography on silica gel
with pet-ether * chloroform and recryatallization yielded
dysidimide as white needle crystals.
The structure of dysidimide was determined by chemi- cal and spectroscopic studies including IR, MS, and ID
and 2D NMR. The relative stereochemistry at C-4 and C-5
was deduced from nOe measurements on/ the 4-Acetate
Description
Keywords
Red Sea Sponge