Magnitude and Predictors of Mortality among Preterm Neonates Admitted in NICU at Debre Markos and Felegehiwot Specialized Hospitals in East and West Gojjam zones, Amhara Reginal State, Ethiopia, 2020; a Retrospective Cohort Study.
No Thumbnail Available
Date
2020-06
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Addis Abeba University
Abstract
Backgrounds: Premature neonatal death is a global burden both in developed and developingcountries. Despite, different strategies and interventions were implemented to reducepremature neonatal complications including death, the rate of neonatal mortality in Ethiopiaare too far from the targets.
The objective: the aim of this study is to determine magnitude and predictors of mortalityamong preterm neonates admitted to neonatal intensive care unit from 2016-2019 in NICU ofDebre markos and Felegehiwot specialized hospitals in Amhara region, Ethiopia.
Method: an institution based retrospective cohort study in two specialized hospitals of Debremarkos and Felegehiwot in East and West Gojjam zones, Amhara regional state, among all432 preterm neonates admitted and enrolled in NICU treatment from 1st of January, 2016 tothe 1st of February, 2019 after getting ethical clearance from Institutional Review board ofAddis Ababa University, College of Health sciences, school of Nursing and Midwifery anddepartment of nursing using a structured checklist to gather information. The data abstractiontool was developed from related literatures with some modification and the neonatal nationalguideline which are currently used in NICU in hospitals. Data was entered into and clearedusing epidata software version 3.1 and then has been exported to SPSS version 24 for furtherstatistical analysis. Data was analyzed using SPSS version 24 for windows. The level ofsignificance was set at P<0.05 with the corresponding confidence intervals at 95%. A logisticregression model was used for analysis and to control for confounders.
Result: The magnitude of mortality among preterm neonates admitted to neonatal intensivecare unit of public hospitals was 160(37%) with (95%CI; 58.8%%,-67.6%). Variables of premature rupture of membrane{AOR: 2.14(95%CI=1.098, 4.20)}, neonatal sepsis{AOR:2.80, (95%CI=1.46, 5.40)}, respiratory distress {AOR: 2.28, (95%CI=1.32, 3.95)}, Perinatalasphyxia{AOR: 2.85, (95%CI: 1.34, 6.10)}, Gestational age of the preterm neonates (28-31weeks){AOR: 2.55, (95%CI=1.356, 4.80)}, low birth weight of 1000-1499 and less than 1000grams{AOR:3.274, (95%CI=1.54, 6.97)} and {AOR: 10.34(95%CI=1.6, 7,20)} respectively)and length of hospital stay less than or equal to one and 2-7days {AOR: 9.63, (95%CI=3.35, 7.70)} and {AOR; 5.45, (95%CI: 2.37, 12.52} )respectively were significantly associatedPredictors of preterm neonatal mortality.
Conclusion: In the current study, a total of 160(37.0%) neonates were died during the followup period. Magnitude of death was found to be high particularly in early neonatal multivariate analysis showed that the major predictors of death of preterm neonates admittedto NICU were found to be premature rupture of membrane, neonatal sepsis, respiratorydistress syndrome, gestational age less than 32 weeks, weight of the preterm neonates lessthan 1500grams and length of hospital stay less than 2 days were found to be significantlyassociated predictors of preterm neonatal death.
Description
Keywords
Magnitude of mortality, predictors, gestational age, Preterm neonate, occurrence of death.