Molecular Characterization and Antimicrobial Susceptibility Profile of Bacterial Isolates From Patients with Surgical Site Infection in Ethiopia: A Multicentre Prospective Cross-Sectional Study
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Date
2024-06-19
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Addis Ababa University
Abstract
Globally, surgical site infections (SSI) are the most reported healthcare-associated infections. The most common pathogens associated with surgical wound infection are Gram-negative bacteria, and Staphylococcus aureus. Antibiotic resistance is increasing annually, and a major challenge in the management of SSI. Despite several reports on phenotypic examinations of bacterial isolates, there are few data on the molecular characterstics and antimicrobial resistance genes of bacteri isolated patients with SSI in Ethiopia.
Objective: The aim of this study was to isolate and determine the antimicrobial susceptibility pattern; genes associated with drug resistance and identify risk factors associated with surgical site infection in Ethiopia
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Keywords
Molecular epidemiology, surgical site infections aetiologies, ESBL, Carbapenemase producing, Multidrug resistance, Risk factors, Ethiopia