Prevalence and Predictors of Meconium Aspiration Syndrome among Neonates Admitted in Governmental Hospitals in Addiss Ababa Ethiopia 2021
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Date
2021-05
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Addis Abeba University
Abstract
Background: - Meconium aspiration syndrome (MAS) is a life-threatening respiratory diseaseoccurring when neonates aspirate meconium-stained amniotic fluid near or around birth withvarying severity. An average of 8% to 25% live birth neonates with meconium-stained amnioticfluid have delivery complications and from these around 5% of them develop MAS with a 50%chance of needing for mechanical ventilation. There is a paucity of literatures in the study arearegarding the study topic. Therefore, the study aimed to assess the prevalence and associated factorsof meconium aspiration syndrome among neonates admitted in NICU of governmental hospitals inAddis Ababa Ethiopia.
Methods: - An institutional based retrospective cross-sectional studydesign was employed to collect data from February to Mach 2021. A three-year chart review fromJanuary 2018 to January 2021 was conducted. The data was collected by using structuredquestionnaire. Systematic random sampling technique was used to involve the estimatedstudy participants (268). Factors associated with meconium aspiration syndrome were determinedusing bivariate and multivariate logistic regression models. Statistically significant associationswere declared at P value less than or equal to 0.05.
Result: The findings from this study revealedthat 30.6% were diagnosed to have meconium aspiration syndrome. Factors associated withmeconium aspiration syndrome included being post term (Adj OR=17.548 95% CI(2.894,106.413)), first minute APGAR score of 7-10 (Adj OR=17.548 95% CI (2.894,106.413)),duration of labor from 12-24 hour (Adj OR=4.98 95% CI (1.677, 14.792)) and maternal bloodgroup of AB (Adj OR=0.118 95% CI (0.029, 0.470).Conclusion and recommendation: In thisstudy almost 1/3 of the neonates had developed meconium aspirarion syndrome which indicatesfor the initiate delivery before 40 completed weeks of gestation and anticipation of neonatalresuscitation for neonates born from blood group of AB mothers.
Key words: -MAS, neonate,respiratory distress and MASF.
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Keywords
Neonates , Meconium Aspiration