Prevalence and Predictors of Meconium Aspiration Syndrome among Neonates Admitted in Governmental Hospitals in Addiss Ababa Ethiopia 2021

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Addis Abeba University


Background: - Meconium aspiration syndrome (MAS) is a life-threatening respiratory disease occurring when neonates aspirate meconium-stained amniotic fluid near or around birth with varying severity. An average of 8% to 25% live birth neonates with meconium-stained amniotic fluid have delivery complications and from these around 5% of them develop MAS with a 50% chance of needing for mechanical ventilation. There is a paucity of literatures in the study area regarding the study topic. Therefore, the study aimed to assess the prevalence and associated factors of meconium aspiration syndrome among neonates admitted in NICU of governmental hospitals in Addis Ababa Ethiopia.Methods: - An institutional based retrospective cross-sectional study design was employed to collect data from February to Mach 2021. A three-year chart review from January 2018 to January 2021 was conducted. The data was collected by using structured questionnaire. Systematic random sampling technique was used to involve the estimated study participants (268). Factors associated with meconium aspiration syndrome were determined using bivariate and multivariate logistic regression models. Statistically significant associations were declared at P value less than or equal to 0.05.Result: The findings from this study revealed that 30.6% were diagnosed to have meconium aspiration syndrome. Factors associated with meconium aspiration syndrome included being post term (Adj OR=17.548 95% CI (2.894,106.413)), first minute APGAR score of 7-10 (Adj OR=17.548 95% CI (2.894,106.413)), duration of labor from 12-24 hour (Adj OR=4.98 95% CI (1.677, 14.792)) and maternal blood group of AB (Adj OR=0.118 95% CI (0.029, 0.470).Conclusion and recommendation: In this study almost 1/3 of the neonates had developed meconium aspirarion syndrome which indicates for the initiate delivery before 40 completed weeks of gestation and anticipation of neonatal resuscitation for neonates born from blood group of AB mothers. Key words: -MAS, neonate, respiratory distress and MASF.



Neonates , Meconium Aspiration