Chemical Constituent of Euclea schimperi
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Date
1988-06
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Addis Ababa Universty
Abstract
There are two indegineous Euclea species in Ethiopia
of a total of nearly 20 species of Euclea in the world
all of which are restricted to tropical and subtropical
Africa, Eucl80 schimJ?erU (family Ebenaceae), known in
Amharic os Dedeho, is used in Ethiopia traditional medicine
for the treatment of gonorrheae.
The extract obtained from the root bark afforded
seven naphthoquinones and two triterpenes, Five of the
naphthoquinones are known compounds, these being 7-methyljuglone
(N-i), neodiospyrin (N-2), 2-methylnaphthazarin
(N-3), mamegokinone (N~4), and isodiospyrin (N-7). The
other two naphthoquinones have not yet been structurally
elucidated, The two triterpenes are lupeol (T-i) and
unidentified triterpene (T-3),
The extract from the stem-bark of g. schimperi
yielded isodiospyrin (N-7), lupeol (T-i), and another
unchar'lcterized triterpene (T-2).
From previous phytochemical reports it appears that
out of the known naphthoquinones isolated neodiospyrin
(N-2) and 2-methylnaphthozarin (N-3) have not been reported
before from any part of the plant. Furthermore,
the occurrence of naodiospyrin (N-2) from the genus
Euclea is reported here for the first time
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Keywords
Euclea schimperi