Assesment of Conorrhoea and Syphilis in Patients Attending Clinics For Sexually Transmitted Diseases in Addis Ababa
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Date
1993-05
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Addis Ababa University
Abstract
In this study a total of 754 individuals were involved. The
study population was divided into 3 ~roups: a/200 (27%) pre~nant
women, b/l05 (14%) students, and c/449 (59%) patients attending
clinics for STDs. Blood samples collected from all members of
the study population, were examined for syphilitic infection. A
seroprevalence of 13%, 11.2% and 21.6% were found among pregnant
"homen, students and STD patients by both RPR and TPHA
respectively. The validity of RPR as a screening test was
determined using sensitivity, specificity, percentage of positive
predictive value and efficiency. Strong positives and positives
by the RPR test can be considered as positive for syphilis. Only
weak positives require retesting. Endocervical and urethral
(male) discharge samples, collected from 233 STD patients in
addition to the blood samples, were examined for the presence of
Neisseria I{onorrhoeae. The organism was isolated from 68 (29.2%)
sub.i ects. Among the isolates, PPNC strains comprised 48 (70%) of
the samples. PPNC strains Were resistant to penicillin (100%),
ampicillin (96%). bactrim (91%) and kanamycin (22%). Of the nonPPNG
strains 25% were resistant to pencillin. 20% to ampicillin,
40% to bactrim and 15% to kanmycin. Both groups were, however.
sensitive to erythromycin, tetracycline, chloramphenicol and
ceftriaxone.
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Biology