Antimicrobial Resistance Pattern of Common Bacterial isolates in Soddo Christian Hospital
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Date
2017-01
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Addis Ababa University
Abstract
Infectious diseases are the leading causes of mortality and morbidity in developing countries.
Management of infectious disease requires potent and effective antimicrobial drugs to which the
virulent organisms are susceptible.. A retrospective cross-sectional study was done by reviewing
1500 microbiology records from September, 2009 to August, 2014. From 1500 microbiology
records, 1086 bacteria were isolated. Among these (4.9%) were mixed infection . The most
common isolated bacteria were S. aureus and P. aeruginosa with an isolation rate of (17.3)
and (14.3%) respectively. About 47.4 % of S.aureus was oxacillin/methicillinresistant
(MRSA).Ontheother hand, the resistance rate of S. aureus was lower to ceftriaxone 172
(19.8%).
S. pyogenes was resistant to tetracycline while lower resistance was observed to
erythromycin,. The highest resistance rate of P. aeruginosa and E. coli were found to
ampicillin and amoxicillin. From multidrug resistant bacteria, majority were gram negative
among which P. aeruginosa (97.7%) was the highest followed by E. coli (95.1%). Among
gram positive MDR bacteria S.aureus (89.1%) was the highest followed by S. epidermidis
(87.5%). The findings of this study show that there is high resistance rate of bacterial isolates to
the commonly used antimicrobials. To benefit maximum antimicrobial effect from the active
antimicrobials and to reserve the threatened ones rational use of antimicrobials should be
practiced.
Key Words: Antimicrobial Resistance, Antibiotic Susceptibility, Bacterial Isolates.
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Keywords
Antimicrobial Resistance, Antibiotic Susceptibility, Bacterial Isolates