Dermatovenorology

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https://etd.aau.edu.et/handle/123456789/4079

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Browsing Dermatovenorology by Subject "ALERT"

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    Quality of life and its Determinants among psoriasis patient
    (Addis Ababa Uinverstiy, 2025) Samrawit Admassu; Genet Tefer; Yoseph Leges
    Psoriasis is a common chronic inflammatory disease characterized by skin inflammation and epidermal hyperplasia. Psoriasis can significantly impact a person's quality of life. Physical discomfort, such as itching, and pain, can interfere with daily activities. The visible nature of the condition can lead to emotional distress, social stigma, and mental health issues like anxiety and depression. People with psoriasis are also at a higher risk for other health conditions, such as psoriatic arthritis, cardiovascular diseases, and mental health issues. Understanding psoriasis and its wide-ranging effects on individuals is essential for providing effective care and improving the lives of those affected by this chronic condition Objective: This study aimed to Quality of life and its Determinants among psoriasis patient at ALERT hospital, Addis Ababa Ethiopia Methods: A hospital-based cross-sectional study was conducted at ALERT Comprehensive Specialized Hospital, Addis Ababa, from May to August 2025. A total of 128 patients aged 16 years and above with a confirmed diagnosis of psoriasis and at least six months of follow-up were included using consecutive sampling. Data were collected through face-to-face interviews using a structured questionnaire and the Dermatology Life Quality Index (DLQI). Sociodemographic and clinical data were recorded. Data were entered and analyzed using SPSS version 27. Due to non-normal distribution of DLQI scores, non-parametric tests (Mann– Whitney U, Kruskal–Wallis H, and Spearman correlation) were applied. Statistical significance was set at p < 0.05. Result: The median DLQI score was 13 (IQR: 9–18), indicating a very large impact of psoriasis on quality of life. More than half of the patients experienced very large to extremely large impairment. Poor quality of life was significantly associated with older age, marital status, social drug habits, family history of psoriasis, early age at diagnosis, pustular psoriasis, and involvement of functionally or socially sensitive sites such as extremities, genitals, palms, soles, and nails. Disease duration, sex, educational status, income level, and most comorbidities showed no significant association with quality of life. Conclusion: Psoriasis has a substantial negative impact on the quality of life of patients attending ALERT Hospital, even among those with mild clinical severity. Quality of life VIII impairment was influenced more by disease characteristics and lesion location than by sociodemographic factors. Routine assessment of quality of life and integrated clinical and psychosocial management approaches are essential to improve patient outcomes.
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    Quality of life assessment in patients with Alopecia Areata
    (Addis Ababa Uinverstiy, 2025) Blen Yosef; Ahmed Mohammed; Mihretu Woldeyes
    Alopecia Areata (AA) is a non-scarring, autoimmune hair loss disease that has the same sex distribution, and an estimated prevalence of 1-6.7 percent by the general population. It is chronic and may greatly diminish quality of life (QoL). Objective: This study was aimed at measuring QoL among AA patients at the ALERT hospital Dermatovenerology clinic in Addis Ababa, Ethiopia. Methods: A prospective cross-sectional study on 68 AA patients (May-Oct 2025). The Dermatology Life Quality Index (DLQI) was used to measure QoL. Checklist was used to gather data and analyzed using SPSS 27. Median (IQR) and frequency (%) are used to present continuous and categorical data, respectively. Tests of associations were performed on Mann Whitney U, Kruskal-Wallis H, and Spearman correlation test (significance: p<0.05). Result: The mean age of the respondents (69.1% females) was 29.4 +- 11.6 years. Most (63.6%) were aged 16-34. The average length of disease was 12.67 +- 15.70 months. Nearly all (97.1%) had patchy AA. The average SALT score was 4.54 +- 3.62; all the cases mild (SALT<25%). Median DLQI score was 7 (IQR: 4-11). Younger age, high SALT score (p=0.043), disease duration (p=0.043), prevalence of scalp involvement (p=0.019) and positive family history were significantly correlated with higher DLQI (worse QoL). Conclusion: AA has a significant effect on deteriorating QoL. The worse impact is associated with the younger age, higher SALT scores, and longer duration of disease, beyond scalp involvement, and positive family history. Psychosocial burden of AA is not only cosmetic and, therefore, needs to be addressed in healthcare.