School of Pharmacy

Permanent URI for this college

http://etd.aau.edu.et/handle/123456789/79

Browse

Browsing School of Pharmacy by Subject "Adherence Antiretroviral therapy"

Now showing 1 - 1 of 1
  • No Thumbnail Available
    Item
    Assessment of level and factors affecting adherence to antiretroviral therapy in Nagelle town, Oromia regional state, Ethiopia
    (Addis Ababa University, 2023-10) Solomon,Tigist; Gedif,Teferi(Prof.); Haile,Mesfin(Dr.)
    Introduction: An adherence level greater than 95% is necessary to get a good outcome out of antiretroviral treatment, and adherence to antiretroviral therapy has also been the strongest predictor of the progression of outcome of antiretroviral therapy. This study intended to assess the level and factors affecting adherence to ART among HIV-infected adult patients in Nagelle town. Method: A cross-sectional study employing both qualitative and quantitative methods was conducted from September 1-30, 2019. A systematic sampling method was used to select the study participants. A total of 285 questionnaires and review of medical records using a semi-structured questionnaire and information capturing sheet were included. Data entry and analysis were performed using SPSS for Windows version 21. Bivariate and multivariate analysis evaluated the association between dependent and independent variables. Thematic analysis was used for qualitative data. Result: The research finding revealed that 69.8% of the study participants had good combined adherence to dose, schedule, and dietary instructions in the past month. Educational status (P=0.035), presence of illness (P= 0.001), use of other drugs (p=0.001), absence of social support (p=0.017), and use of alcohol (p=0.001) were found to be significantly associated with poor adherence to ART. Having good relations with health care providers, the Perceived benefit of adherence by HCP, and long refill appointments were identified as facilitators of adherence. The barriers include stigma and discrimination, lack of skilled HCP, distance to health facilities, and use of other drugs. Conclusion: This study found that participants' education status, presence of illness, use of other drugs, social support, and drinking alcohol were determinant factors that affect adherence to antiretroviral therapy. Interventions are recommended to improve the adherence of patients to antiretroviral therapy.