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Item Acceptance of Electronic Medical Record System and Associated Factors among Health Professionals Working at Public Health Facilities in Addis Ababa, Ethiopia: a Mixed Methods Approach(Addis Ababa University, 2025-06) Adisu,Amanuel; Taye,Girma(PhD); Yilma,Mengistu(MPH, PhD Fellow)Background: Electronic Medical Records (EMRs) can potentially enhance the overall quality of healthcare services, including the availability and reliability of health information. Health professionals' computer literacy, willingness, knowledge, and attitudes toward Electronic Health Records significantly impact the acceptance and adoption of the EMR. Examining health professionals' acceptance and identifying barriers to EMR usage can provide valuable insights for recommendations to strengthen EMR implementation in healthcare settings. Objectives: To assess the acceptance level of EMRs and associated factors among Health Professionals working at public health facilities in Addis Ababa City Administration, Ethiopia, 2024/25 Methods: A cross-sectional study with both quantitative and qualitative approaches was carried out among 475 health professionals who worked at Addis Ababa's public health facilities during the study period. Face-to-face interviews using an electronic structured questionnaire were used to gather data, which was subsequently filtered for errors and missing values. The quantitative analysis was conducted using STATA version 17.0, and the qualitative analysis was conducted using Open Code version 4.03. Adjusted odds ratios with a 95% confidence interval were estimated using binary logistic regression and descriptive statistics. A p-value of less than 0.05 indicated that a variable was statistically significant. Result: Among 475 health professionals, 61.47% (95% CI: 57.08-65.87%) had good acceptance of Electronic Medical Records (EMRs). Key predictors included favorable attitude, good computer skills, adequate knowledge, and willingness to use. Challenges include lack of power and connectivity, system disruption, resource limitation, inadequate training and personnel resistance of the system. Conclusion: The findings revealed that 61.47% of respondents expressed a good level of EMR acceptance, driven by a favorable attitude, solid knowledge, strong computer skills, and a willingness to use the system. However, power outages, unstable internet connectivity, a lack of standard operating procedures, insufficient technical support, and the dual documentation burden (paper and electronic systems) hinder widespread adoption. Recommendations include infrastructure improvement, standardized guidelines, policy integration, training, and further research.