Browsing by Author "emberu, Dirshaye"

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    Chemical Composition of Croton Macrostacrys
    (Addis Ababa, 1981) emberu, Dirshaye; Abegaz Berhanu (PhD)
    The root- bark powder of Croton macrostachys Hochstex. A. Rich . (Euphorheaceae) ( n nCj') , used in Ethiopia for curing spreading wounds, was extraced with diethyl ether . The crude extract, on fractionation by column chromatography (Silica gel) yielded a major solid compound A (mp 210- 212o ) crystallizable from acetone- methanol (9 ; l) into be autiful needle aggregates, the structure of which was identified , using I R, PHR and MS data , to be that of lupeol , aknown antitumor agent. The tumor inhibitor y compound Crotepoxide which was previously isolated from the fruits could not be detecte in t he rootbark extract. Preliminary investigation also showed the presence of trace solids B and C having the same Rf on TLC. B was water isoluble white solid while C was water soluble and showed strong blue fluorescence unde r UV- I amp. The presence of quaternary alkaloid was also confirmed in the root- bark .