Browsing by Author "Woretaw, Anmut"

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    Thirty Days Posoperative Outcome After Radical Cystectomy and Associated Factors at TASH, Ethiopia.
    (Addis Ababa University, 2025-07) Woretaw, Anmut; Bekele, Seyefe (Ass.Prof.); Melaku, Admasu (Ass.Prof.)
    Background: radical cystectomy is one of the complex and technically demanding urologic surgeries. It is done usually for non-metastatic muscle invasive bladder cancer. Globally the morbidity and mortality rate is significantly high, even the advancement of operative techniques doesn’t change the outcome significantly. And, the outcome of RC is not well studied in Ethiopia including in the study area. Objectives: The objective of this study was to assess the thirty days postoperative outcome of open radical cystectomy and associated factors among patients who were operated at Tikur Anbesa Specialized Hospital. Method: Institution based cross sectional retrospective study was conducted on consequently selected patients who were operated in Tikur Anbesa Specialized Hospital from September 2020 to May 2025. Data was collected using Kobotoolbox from the patients’ medical records. Then exported to Excel and exported to SPSS version 25 after cleaned. Subsequently descriptive analysis and binary logistic regression was done. Association between independent and outcome variables studied using multivariable logistic regression. Variable with p –value <0.05 was used to declare the level of significance. Result: A total of 35 cases were analyzed the average age was 55.54 years. Male sex accounts for 74.3%. ONB was done in 25.7% whereas the rest was IC. 45.7% of the operated patients were with smooth post-operative course others developed minor and major complications. Pre and post-operative biopsy showed 32 cases were urothelial cancer whereas 3 cases were non-urothelial cancer.in 22 cases post-operative biopsy was found and marginal status define. Of these 22 cases 68.2% was margin positive. There were about 4 deaths early post operatively due to surgical causes. Multivariable regression analysis showed serum albumin level <3g/dl was associated with post-operative complication with p-value of 0.019 and adjusted odds ratio of 14.54. Conclusion: The 30 day mortality and morbidity rate were 11.4% and 54.3% respectively. Serum albumin <3g/dl was associated with post-operative complication.