Browsing by Author "Woldesenbet, Deribe"

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    Assessment of Medicine use and associated outcomes among pregnant women visiting antenatal care units in Public Health Facilities in Butajira, South Central Ethiopia
    (Addis Abeba University, 2020-09) Woldesenbet, Deribe; Prof. Gedif, Teferi (B. Pharm, MPH, PhD); Ashenef, Ayenew(Msc)
    Introduction: Medicine use during pregnancy is a growing trend in the world. Medicines easily cross the placental barrier into the fetal body and are present also in the maternal milk. Exclusion of pregnant women from clinical trials has left questions about the safety of medicines in pregnancy. There were no such studies which assess the medicine use pattern and associated outcomes among pregnant women in Butajira. Hence this study attempted to fill such gaps. Objective: To assess medicine use pattern and associated outcomes among pregnant women visiting antenatal care unit in public health facilities in Butajira. Methods: Institution based prospective cohort study design was employed by interviewing pregnant women who were on routine antenatal care visit and waiting them until they give birth. Study participants were waited from March, 2018-November, 2018. Interview included recent medicine use history. Clinical data was obtained by abstracting the records of women who attended Antenatal Care follow up. Result: A total of 399 pregnant women were included in this study, of whom 382(95%) of them had taken at least one medicine during pregnancy, and 24(6%) of them had self-medicated themselves. From prescribed medicines for pregnant women, Iron with folic acid was the most (937, 71.5%) prescribed medicine while Zingeber officinale; ginger was the most (4, 36%) used traditional medicinal herbs used by the pregnant women. Medicines were prescribed from all FDA pregnancy risk categories. In this regard, from the total of medicines used by pregnant women, 978(73.3%) were from FDA pregnancy category A, 194(14.5%) were from category B, 128(9.6%) were from category C, 25(1.9%) were from category D, and 1(0.08%) were from FDA pregnancy category X. From 377 study participants with outcomes of pregnancy (Apgar score, birth weight and term of delivery); 56(15%) had poor pregnancy outcomes while 321(85%) had good pregnancy outcomes. Conclusion: The majority of the study population used safe and appropriate medications. However, though low, a limited number of pregnant women were exposed to medications with potential risk for the fetus. Besides, although few, pregnant women reported the use of traditional medicinal herbs for which pregnancy risk level was not assigned. No statistically significant association was observed between medicines used in this study and pregnancy outcomes.