Browsing by Author "Taffa, Negussie"

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    Malaria in Pregnancy in Three Woredas of East Shoa
    (Addis Abeba Universty, 1994-05) Taffa, Negussie; Ali, Ahmed (PhD)
    A cross-sectiona l, community based study of malaria was condu c t ed from September-December 1993 , in an un stab l e ma laria endemi c area in Eastern Shoa , Ethiopia, to determine the prevalence and document the c l inical features and treatment responses in pregnant and non pregnant women. A total of 1,767 women were studied. Ninety (11.3%) pregnant and 63{6.6%) non pregnant women were found to have malaria parasitemi a (P=O.OOl). The rate in primigravidae was hi gher than in multigravidae, 212(12.24%) and 31 4{11 .4%) respectively, though the difference was not sta ti stical ly s igni ficant. Overa ll Plasmodial prevalence showed 49.7% Plasmodium v i vax and 50.3% Plasmodium falciparum. Mean gestat ional age o f the pregnant women was 21.09± 10.2 weeks wi th Peak malari a parasitemia around mid- pregnancy. Maj ority of cases were symptomatic during diagnosis and symptoms were not different between pregnant and non pregnant. Conjun ct i va l pallor was more documented in pregnant than in non pregnant (OR = 3.04, 95% CI.1.47,6 . 33). Mean haematocrit in the pregnant was 30.3± 4.6% a nd 33.4± 6.8% in the non pregnant (P= 0.000 1) . Primigravidae showed lower haematocrit va lues a nd higher mean parasite counts when compared to multigravidae (P =0.03 and 0.06 respectively). Mean asexual malaria parasite count was 6, 561± 5,259/micro litter of blood and 4,598± 4,275/micro litter of b l ood in pregnant and non pregnant respectively (P= 0.01). ix Clinical responses in both groups were not signi f icantly different. Findings are discussed and recommendations made regarding future studies.