Browsing by Author "Tadesse Daniel"

Now showing 1 - 1 of 1
  • No Thumbnail Available
    Item
    Incidence of Paravalvular Leak and Prosthetic Valve Stuck with in 30 Days After Open Heart Valve Replacement Surgery Retrospective Study in Addis Ababa,Ethiopia,2025.
    (Addis Ababa University, 2025-01) Tadesse Daniel; Abebe Yonatan
    Introduction: Valvular heart disease (VHD) remains a critical global health burden, with causes differing by region: age-related degeneration dominates in high-income countries, while rheumatic heart disease (RHD) drives cases in sub-Saharan Africa, particularly Ethiopia. Open-heart valve replacement, the primary intervention in Ethiopia, faces challenges such as limited access to advanced technologies, inconsistent anticoagulation monitoring (e.g., INR), and inadequate follow-up. Early postoperative complications—paravalvular leak (PVL) and prosthetic valve thrombosis ("stuck valve")—are life-threatening yet understudied in Ethiopia, despite their high incidence linked to resource constraints and surgical limitations. This study investigates the 30-day postoperative incidence of PVL and valve thrombosis in Ethiopian patients, aiming to inform strategies to reduce complications and improve outcomes in low-resource settings. Objective: To assess the incidence of paravalvular leak and prosthetic valve thrombosis (stuck valve) within 30 days following open-heart valve replacement surgery in Ethiopia. Methodology: An institution-based retrospective study design will be conducted to determine the immediate outcomes of patients who underwent valve replacement surgery during the designated data collection period. The sample size was calculated to be 192 using a population reduction formula. The data collection process will be organized and led by the Principal Investigator (PI). Patient charts will be reviewed to extract pertinent clinical data from the participants. Before commencing the data collection process, the study objectives will be clearly explained to the respective personnel responsible for managing the medical charts.