Browsing by Author "Sisay, Abay (MSC, PHD fellow)"

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    Assessment of Laboratory Service Interruption and its Associated Factors in Public Hospitals, Addis Ababa, Ethiopia
    (Addis Abeba University, 2020-11) Mulu, Tilanesh; Urgessa, Fekadu(MSC, Assistant professor, PHD fellow); Sisay, Abay (MSC, PHD fellow)
    Background: Medical laboratory service is very essential for sustainable and reliable patient diagnosis and treatment. Interruption is a global problem and much higher in resource limited settings. However, there is no adequate evidence on the magnitude and contributed factors. Thus, this study aimed to assess the laboratory service interruption and its associated factors in public hospitals found in Addis Ababa, Ethiopia. Methods: Facility based cross sectional study design was conducted in public hospitals found in Addis Ababa using qualitative and quantitative data from April-June/ 2020in Ethiopia. Standardized check list was developed to assess level of interruption and also structured dichotomous questioners’ were used for related factors. Data was entered and analyzed using SPSS version 23. Binary and multiple logistic regression analysis were used to explanatory factor that affect the outcome variable. Result: Totally 190 laboratory professionals were participated with a response rate of 95.5%. In public hospitals averagely 17(23%) tests were interrupted for 76(84%) days. In specialized and General hospitals averagely 13(17%) and 19(28%) tests were interrupted, respectively. In this study serology and hematology tests accounts the highest level of interruption which is 5(6.9%) and 4(5.5%) respectively. While parasitological, urinalysis and body fluid analysis were consistently available. Absence of laboratory annual plan at [AOR=3.028, pvalue=0.044, 95%Cl (1.030-8.903], inappropriate equipment maintenance at [AOR=9.350, pvalue=0.003, 95%Cl (2.102-41.596], and shortage of reagents and supplies at [AOR=3.845, pvalue=0.049, 95%Cl (1.008-14.663] were the major factors that affect laboratory service interruption. Conclusion: Even though sustainable laboratory service is important in the health care service, most public hospital laboratories found in Addis Ababa did not provide continuous diagnostic service for all expected tests. Therefore, to improve service interruption, hospital managers, health professionals and other stakeholders should undertake effort to intervene the factors that affect laboratory service interruption.
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    Assessment of Reasons for Service Interruption and Unsuccessful Test Results Related to GeneXpert Diagnostic Service in Addis Ababa Public Health Facilities.
    (Addis Abeba University, 2021-01) Merkebu, Mesafint; Sisay, Abay (MSC, PHD fellow); Hassen, Fatuma( BA, BSc, MPH, PhD Candidate)
    Background: Tuberculosis (TB) was one of the top 10 causes of death worldwide in 2018. It is also the leading killer of people with HIV and a major cause of deaths related to antimicrobial resistance. Ethiopia is among the 30 high burden tuberculosis countries, with annual estimated TB incidence of 151/100,000 population and HIV negative TB mortality of 22/100,000 population as of 2018 global TB report. At present, the major problem in managing TB is lack of an accurate and rapid diagnostic test. Accordingly, rapid diagnostic test for detection of TB and rifampicin resistance currently available is the GeneXpert assay as WHO recommended. However health facilities which having GeneXpert diagnostic device encountered different challenges during implementation. Objective: This study was aim to assess the reasons for service interruption and Unsuccessful test results related to GeneXpert diagnostic service in Addis Ababa public health facilities. Methods: Cross sectional study design was conducted in public health facilities which provided GeneXpert diagnostic service in Addis Ababa, Ethiopia. Quantitative and qualitative questionnaires based data was collected from January to March 2020. The data was cleaned, entered and analyzed using SPSS version 20 at a statistical significance of P value ≤ 0.05 using logistic regression. While the qualitative data obtained was summarized in thematic narrative form. Results: Reasons of GeneXpert diagnostic services resulted to service interruptions and unsuccessful test results identified in this study. At least once or more than one times of service interruption of GeneXpert were occurred in 82% of the health facilities in the study period. Service interruption were dependent on the stock out of cartridge ( X2 =10.6, p value <0.01). While, a total of 4% (1078/26998) unsuccessful test result were occurred, of which 2.3% (618/26998) was due to ‘Error’ followed by ‘No result’ 1.2% (334/26998) and ‘Invalid’ 0.5% (126/26998). Conclusion: The main reasons of GeneXpert diagnostic service which resulted to service interruptions were stock out of cartridge, machine down, system failure, module failure and cartridge malfunction. In the other hand, insufficient sample volume, power interruption, poor sample quality, food contaminant and technical errors were reasons for unsuccessful test result. Thus, sustainable power supply, responsive maintenance support, sustainable supply chain system and refresher training are at most important.