Browsing by Author "Saron Tamire"

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    Blood and Blood Component Wastage Rate: Associated Factors in Ethiopia Blood and Tissue Bank Service and Selected Hospitals, Addis Ababa, Ethiopia.
    (Addis Ababa University, 2025-06-07) Saron Tamire; Daniel Beshah; Fatuma Hassan
    Background: Blood is an invaluable resource essential to human survival, making blood transfusion a critical, life-saving procedure: therefore: - blood transfusion can be a life-saving intervention. Discarding or wastage of blood can be attributed to several reasons namely expiration, Transfusion Transmitted Infection, storage problems, inaccurate volume collection, broken bags and seal with leakage, hemolytic reasons, clotted blood, lipemia, greenish or yellowish, discoloration, contamination, returned after 30 min and not used ordered blood. The main aim of this study is to assess the rate of blood wastage and associated factors at Ethiopia Blood and Tissue Bank Service and selected hospitals in Addis Ababa, Ethiopia during 2024/2025. Methods: A facility-based cross-sectional study was conducted in Ethiopia Blood and Tissue Bank Service and selected hospitals in Addis Ababa. Three-month retrospective and three-month prospective data were collected by using a structured checklist from November 2024 to April 2025. The total blood and blood components issued were 84,501 units. A questionnaire was developed from assessment tools and a total of 105 professionals were participated. After verifying the completeness, the data were coded and entered into SPSS software for analysis. The association of variables was also analyzed using a bivariate and multivariate logistic regression analysis. Three key personnel were interviewed for qualitative data and analyzed using a thematic approach to illustrate the findings. Result: A total of 48,235 units of blood were collected in Ethiopia Blood and Tissue Bank Service within six months. Of the total blood units 31,444 were kept as Whole Blood, and the remaining 16,791 blood units were made into components such as 16,207 Packed Red Blood Cells, 14,115 Platelet Concentrate and 14,115 Fresh Frozen Plasma. The total numbers of blood units issued during the study period were 75,881 from this blood wastage rate was 7,738 (10.15%) with 8,298,866.68 Ethiopian birr from November 2024 to April 2025; The highest wastage was observed in Fresh frozen plasma 3,355 (4.4%) units discarded, followed by Whole Blood 2,812 (3.7%), Platelet Concentrate 1,075 (1.4%), and PRBC 496 (0.65%). A total of 8,620 blood units were received by Tikur Anbessa Specialized Hospital and Myung sung Christian Medical Center within six months. Of the total of blood units received: - 1,556 were whole blood, 3,140 were Packed Red Blood Cells, 2,499 were Platelet Concentrate, and 1,425 were Fresh frozen plasma of x this blood wastage rate was 229(2.6%), with 245,638.24 Ethiopian birr from November 2024 to April 2025. The highest wastage was observed in whole blood 93(1%) followed by Fresh Frozen Plasma 66(0.7%), Packed Red Blood Cell 40(0.46%), and Platelet Concentrate 30(0.34%). Expiry date, Transfusion Transmitted Infection, Improper storage, Inaccurate blood collection volume, and Lack of pediatric blood bag show a significant association with blood wastage rate, P < 0.05. Conclusion: The study found a blood and component wastage rate of 10.15% at EBTBS and 2.65% at selected hospitals, with a total cost of around 8.5 million ETB from November 2024 to April 2025. From the components, Fresh frozen plasma had the highest wastage rate. Key factors associated with wastage included expired units, transfusion-transmitted infections, improper storage, inaccurate collection volume, and lack of pediatric blood bags. Notably, the discard of partially used pediatric units due to the absence of pediatric bags was a significant issue, highlighting a critical gap affecting a vulnerable patient group.