Browsing by Author "Samuel, Hirbo (B.Sc. M.Sc."

Now showing 1 - 1 of 1
  • No Thumbnail Available
    Item
    Comparison of Perioperative Blood Glucose Concentration in Spinal Versus General Anesthesia in Patients Undergoing Elective Lower Abdominal and Pelvic Surgery at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia,2020/21:A Prospective Cohort Study.
    (Addis Abeba University, 2021-06) Negash, Mestawet; Girma, Betelihem(B.Sc. M.Sc. ; Samuel, Hirbo (B.Sc. M.Sc.
    Introduction: Surgery is linked with fear and stress that disrupt metabolic and neuroendocrine activities which impair normal maintained glucose metabolism that leads in stress hyperglycemia. Anesthesia inhibits the stress responses and hyperglycemia but the mechanism at which they reduce surgical induced hyperglycemia is different. Objective: This study compares the effect of GA and SA on perioperative blood glucose levels in patients that undergo lower abdominal and pelvic surgery at Tikur Anbessa Specialized Hospital. Method: An institutional-based prospective cohort study was done on 70 individual patients; 35 in each group that undergo lower abdominal and pelvic surgery under GA and SA by using a systematic random sampling technique. Capillary blood glucose was measured 4 times: T1; 5 minutes before induction in GA and giving SA, T2; after 5 minutes of induction in GA and complete block in SA, T3; immediately at the end of surgery in both groups and T4; 60 minutes after the end of the surgery in both groups. Collected data were entered into SPSS version 24 and the normality was checked by the Shapiro Wilk test. For statistical analysis unpaired t-test and paired t-test were used to compare the mean of normally distributed data between the two groups and within the group respectively, presented by mean and standard deviation. Manny Whitney U test was used for asymmetric data and presented by median and interquartile range. Categorical data were presented by percentage and analyzed by chi-square test. P values <0.05 were considered statistically significant. Result: No statistically significant difference was observed in mean blood glucose levels at T1 and T2 between the two groups. But at T3 (GA:115.57 ± 16.60 vs. SA:104.34 ± 14.06, p= 0.005) and T4 (GA;117.34 ± 16.79 vs. SA;106.00 ± 14.57, p=0.004) the mean blood glucose levels were statistically significantly higher in the GA group than SA group and when compared to the baseline. The incidence of stress hyperglycemia under GA was 34.3% compared to 8.6% under SA. Conclusion and Recommendation: SA reduces the incidence of stress-induced hyperglycemia as compared to GA in patients undergoing lower abdominal and pelvic surgery. We recommend SA over GA whenever possible for patients undergoing lower abdominal and pelvic surgery.