Browsing by Author "Nibret, Yonas"

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    Assessment of adequacy of surgical resection for colorectal cancer at Tikur Anbessa specialized hospital from2016-2019, Addis Ababa, Ethiopia.
    (Addis Abeba University, 2020-10) Nibret, Yonas; Seyoum, Nebyou(MD, Associate Prof. of Surgery); Kotisso, Berhanu(MD, Prof. of Surgery)
    Background: Colorectal carcinoma is a malignant neoplasm of the colon and rectum. It is the most common malignancy of the gastrointestinal tract. The enbloc removal of the presenting malignancy, to include adequate margins plus the lymphatic nodal basin, remains the hallmark of surgical treatment for cure. Adequate lymph node evaluation is required for proper staging of colorectal cancer, and the number of lymph nodes examined is associated with survival Objectives: To determine the adequacy of surgical resection of patients operated for colorectal cancer at Tikur Anbessa Specialized Hospital. Methods: A retrospective cross-sectional study was conducted by a review of the medical records of all patients who had undergone resection of colorectal cancer at Tikur Anbessa Specialized hospital from January 1, 2016 to December 31, 2019. The data was obtained from the patient’s record review; data was collected using a pretested questionnaire and checklist. Data were checked and entered into Epi data version 3.1 then exported to statically package for social science version 24 for analysis. Result: From the total of study participants above the half 48(53.3%) are male, with male to female ratio of 1.14:1. The majority 44(48.9%) of study participants were found in the age groups of <50 years followed by 50-64 years 26(28.9%).The mean of LN harvested was 10.35(SD ±7.86) with a maximum of 41 and a minimum of 0.And only40% of patients had Adequate LN harvested (≥12). female patients were 2.12 times more likely to have adequate LN harvested as compared to male patients with AOR=2.12(1.49-3.96). Similarly, patients found in the age group of ≥65 were less likely to have adequate LN harvested as compared to patients found in the age group of <50 years with AOR=1.22 (1.60-4.88). Those patients with an age group of ≥65 years were 2.04 times more likely to have radial Margin involvement as compared to others, while fixed tumors are 2.81 times more likely to have radial margin involvement relative to mobile tumors. Conclusion: In this retrospective study, we described the adequacy of nodal harvest in colorectal cancer and evaluated possible factors that may affect the adequacy nodal harvest. Only 40 % of the patients in this study have adequate nodal harvest based on current guidelines. Younger patients less than 50 years of age and female patients were associated with improved nodal harvest. In this study, age≥65 years and fixed tumors are more likely to have radial margin involvement.