Browsing by Author "Mulugeta, Sofia"

Now showing 1 - 1 of 1
  • No Thumbnail Available
    Item
    A Cross sectional study of Chest metastasis patterns of all malignancies presented to radiology department at Tikur Anbesa Specialized Hospital, Addis Ababa University, Addis Ababa, Ethiopia from October 2018 – May 2019.
    (Addis Abeba University, 2019-10) Mulugeta, Sofia; Gissila, Azmera(MD, Assistant Professor of Radiology); Alwan, Amir (MD, Assistant Professor of Radiology)
    Back ground: Chest is one of the commonest metastasis site of the thoracic or extra thoracic malignancies and Pulmonary metastases have widely variable presentation on imaging and may simulate primary lung tumor or nonmalignant diseases. Therefore, it is important for the radiologist to be familiar with the full spectrum of findings to facilitate correct diagnosis and this study has tried to look for the pattern of chest metastasis. Objective: This study aimed to assess the overall chest metastasis patterns of both thoracic and extra thoracic malignancies and their possible histologic correlation. Methods: A prospective cross sectional study of 202 patients was done from October 2018- May 2019. A structured questionnaire was used to collect data for analysis. Results: of the total 202 cases there are 25 primary sites and the majorities come from the following sites in the descending order esophagus (63), breast (47), lung (24), bones (14), soft tissues (10), thyroid (9), head and neck (11) and miscellaneous (24). The commonly seen histologic variant is Squamous cell carcinoma (46 cases); majority from the esophagus followed by Adenocarcinoma (26 case); majority from the breast and the lung followed by sarcomas (24 cases) mainly from the bones and soft tissues and other miscellaneous histologic variants account 16cases from different sources. For the rest of cases the histology is not known. The commonest metastatic site is found to be the lung parenchyma and air ways (accounting 120 cases with multinodular pattern being the commonest (67cases). The second is found to be the mediastinum accounting 108 cases mainly involving the lymph nodes (106 cases). The 3 the pleura (58 cases) with the pleural nodule being the predominant pattern (24 cases). The last is chest wall metastasis accounting for 53 cases mainly involving the bones (26 cases). There is statistically significant positive correlation seen between the calcific metastasis and sarcomas but no statistically significant correlation between other histologic types and lung metastasis pattern. Conclusion: In both thoracic and extra thoracic malignancies lung parenchymal and air way metastasis is the commonest with multinodular pattern followed by lymphatic spread. The others 2 rd site is are mediastinal, pleural and chest wall metastasis respectively. Calcific metastasis has significant positive correlation with sarcomas.