Browsing by Author "Diriba, Ketema"

Now showing 1 - 1 of 1
  • No Thumbnail Available
    Item
    Anti- Retoviral Therapy Adherence Among Hiv-Infected Children Aged 2-14 Years in Tikur Anbessa Sepcialized Hospital, Addis Ababa, Ethiopia
    (Addis Ababa University, 2015-06) Diriba, Ketema; Mengistu, Zuriyash (PhD)
    Background: Adherence to antiretroviral therapy (ART) is a strong predictor of progression to AIDS and death. The fact that a nearly perfect adherence is required in ART has remained a major challenge to people infected with HIV. Consequently, non-adherence to the proposed antiretroviral regimen is considered to be one of the greatest dangers to the response to treatment on an individual level and the dissemination of resistant viruses on the community level. Objectives: - The aim of the study was to identify the adherence level and associated factors with adherence to ART among HIV infected children aged 2- 14 years in Black Lion Specialized Hospital ART clinic, Addis Ababa, Ethiopia. Method: - A cross-sectional study was conducted between April and May, 2015 in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. A total of 190 children aged 2-14 years on first line ARV regimen for at least six month were included in the study. The registered list of the children on ART by unique ART registration number was used as sampling frame. Data was collected by using interview with structured questionnaire. Ethical clearance was secured from Addis Ababa University College of health sciences institutional ethical review board. The collected data was cleaned, checked for quality, coded and analyzed by using manual and statistical methods, logistic regressions were computed. Odds ratios were computed to determine the level of significance. Result: A total of 190 children were included in this study, and 89.8% of the participants had taken their prescribed ARV drugs fully for the past 7 days. Considering individuals who had ever missed their dose regardless of time reference, overall adherence rate 87.75% was obtained. Although most frequently mentioned reason of missing their dose in the last one week was forgetting (48.1%), ADRs, Quarrel among family are also found to be barriers to adherence. After controlling the effects of other variables, two variables namely income and occupation were found to be significantly associated with adherence to ART in children. Conclusion: Adherence rate obtained in this study is lower than what is required. Forgetfulness, ADRs, and quarrel among family were most frequently mentioned barriers of adherence. Income and occupation are factors found to be significantly associated with adherence to ART in children