Browsing by Author "Digesa Lankamo"

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    Determinants of Multi-Drug Resistant Tuberculosis Among Patients Attending Anti-Tuberculosis Treatment from Peripheral Districts, Southern Nations, Nationalities and Peoples Region, Ethiopia, 2019
    (Addis Ababa University, 2019-06) Digesa Lankamo ; Tachbele Erdaw(PhD); Sr.Hailu Aklil (MSc)
    Introduction The emergence of multi-drug resistant tuberculosis (MDR-TB) is a challenge for the global prevention and control of the disease. Ethiopia is one of the 30 MDR-TB burden countries.Addressing underlying risk factors is one of the principal ways to prevent drug resistant TB. Moreover, there is little research evidence of MDR-TB from the peripheral areas of the country. Objective: to identify determinants of MDR-TB among patients attending anti tuberculosis treatment from peripheral districts, Southern Nations, Nationalities and People Region, Ethiopia,2019. Methods: Hospital based case control study was conducted from March to April, 2019 in Southern Ethiopia. Cases were confirmed MDR-TB patients, while controls were those who declared cured or completed first line ant-TB treatment. Stratified random sampling technique was used to recruit study participants. The data were entered into Epi data 4.4.3, cleaned and analyzed by SPSS 24. Bivariate and multivariable analyses were used to identify determinants of MDR-TB. Determinants with P-value <0.05 were declared as having significant association with MDR-TB and OR with 95% CI was used to measure a degree of association. Result: A total of 180 respondents (90 cases and 90 controls) participated in this study.Uneducated(AOR:4.91,CI:1.63-14.81),rural residence(AOR:2.36,CI:1.03-5.43),BMI<18.5kg/m2 (AOR:3.07,CI:1.42-6.62),pulmonary TB(AOR:4,CI:1.15-13.99),contact history with TB patient (AOR:3.72,CI:1.66-8.30) and history of previous treatment ((AOR:10,CI::4.32-23.16)were found independent determinants of MDR-TB. Conclusions and recommendations: Uneducated, rural residence, BMI<18.5kg/m2, pulmonary TB, contact history with TB patient and a history of previous treatment were associated with MDR-TB. A community level education to enhance public awareness about MDR-TB,nutritional counseling and support; strengthening contact tracing strategies and DOT strategies with treatment adherence interventions were recommended.