Browsing by Author "Asgele Tsehaye"

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    Hematological Indices of Adult Cancer Patients Exposed to Chemotherapy, in Ayder Comprehensive Specialized Hospital, Mekelle, Northern Ethiopia, 2020.
    (Addis Ababa University, 2020-10-19) Asgele Tsehaye; Abebaye Aragaw
    Background: Cancer is one of the fastest-growing diseases throughout the world and it is an emerging public health issue in Africa. Cancer and chemotherapy can directly result in or exacerbate myelosuppression by suppressing the process of hematopoiesis. Objective: This study was designed to determine haematological indices of adult cancer patients who were exposed and not exposed to chemotherapy, in Ayder Comprehensive Specialized Hospital (ACSH), Mekelle, Northern Ethiopia, 2020. Methods: Institutional-based comparative cross-sectional study design was conducted using a convenient and quota sampling method to assess haematologic indices among patients attending the oncology clinic who were exposed and not exposed to chemotherapy, in ACSH, Mekelle, Ethiopia from January to June 2020. The socio-demographic and clinical characteristics of 72 cancer patients were assessed. Structured questionnaires, hospital medical records of study subjects, and Sysmex XT-4000i automated hematology analyzer for CBC analysis were considered. Independent-sample T-test was used to compare the mean values of variables. Binary logistic regression analysis was considered to identify determining factors. Results: Nearly one-half of the study subjects (45.8%, n=72) were found to have anemia in unclassified cancers (exposed group: 58.3%; non-exposed group: 33.3% with P