Browsing by Author "Amin Ilili"

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    Hypoxic Ischemic Encephalopathy; Late Magnetic Resonance Imaging Findings Correlated with Clinical Findings, at Yehuleshet Specialty Clinic, December 2023, Addis Ababa, Ethiopia.
    (Addis Ababa University, 2023-12) Amin Ilili; Debebe Tequam; Saleh Amal; Mekonen Abebe; Endale Tewdros
    Introduction: Neonatal Hypoxic Ischemic Encephalopathy is a brain injury that occurswhen oxygen or blood flow to the brain is reduced or stopped before, during, or shortly afterbirth. Birth asphyxia is the main contributor to both long-term neurodevelopmental problems andinfant mortality in low- and middle-income nations. MRI examination can assist in elucidating the type of injury, the timing of injury, the pattern of pathological evolution, and changes inbrain metabolism over time. Objectives: To explore the late Brain MRI patterns and associated clinical findings of childrenwho had clinical diagnosis of perinatal asphyxia in Addis Ababa, Ethiopia. Methodology: The study is conducted in pediatric neurology clinic with MRI facility in Addis Ababa, Ethiopia. A total of 797 pediatric patient’s charts were identifiedwho had Brain MRI imaging evaluation. Of these, 70 cases with clinical diagnosis of perinatalasphyxia were included. Using a structured questioner, demographic data, pre and perinatalhistory of patients was collected. The MRI reports were reviewed by the principal investigator in a systematic pattern. Result: The age at time of MRI evaluation ranges from 2 months to 14 years. Gestational age was assessed of which 74.3% are term and 25.7% are preterm. 42.9% of our patients received antenatal care (ANC) during gestation and 55.7% were delivered at a healthcare facility GlobalDevelopmental Delay (GDD), observed in 61.4% of the cases followed by Seizures occurring in21.4% of patients. 62.5% of preterm infants had periventricular leukomalacia on MRI as compared with those full-term (10.8%) infants, (P-value<0.001). And, (64.9%) of term infants had Subcortical/ deep watershed border zone hyperintensities on MRI as compared to with preterm (12.5%) infants. MRI findings suggestive of chronic injury, thinning of corpus callosum and cerebral cortical atrophy were seen 31.35 & 40% and 31.3% 37.3% respectively in preterm and term infants. Conclusion: The study reveals high magnitude of perinatal asphyxia (8.8%) among pediatric Neurology clinic visits. Brain MRI imaging showed abnormality in majority of cases with specific dominant patterns seen being periventricular leukomalacia and subcortical/deep watershed hyperintensities for preterm and term infants respectively indicating that brain MRI should be used as primary diagnostic work up for these patients.
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    Imaging Patterns of Laryngeal Cancer on Cross Sectional Imaging & Correlation with Laryngoscopy Findings at Tikur Anbessa Specialized Hospital from 2017-2019
    (Addis Abeba University, 2019-12) Amin Ilili; Saleh Amal ; Assefa Getachew
    Introduction :Head and neck cancer is the commonest cancer among male patients & third commonest cancerin females in a study done at Tikur Anbessa specialized hospital but there is no research done toassess imaging patterns of laryngeal cancer and this is the first study done at Tikur Anbessaspecialized hospital as well as in Ethiopia to assess imaging patterns of laryngeal cancer. Methods :Hospital based descriptive cross-sectional study was used at Tikur Anbessa specialized hospitalfrom 2016-2019. The study participants were all patients with laryngeal mass who came tooncology department & radiology department at TASH. Data was collected from cancer registryin the oncology department as well as by reviewing imaging reports of patients withlaryngeal mass who came to radiology and oncology department using structured questionnaire. The datawas analyzed using SPSS software version 24.4 and results presented using text, tables andgraphs. Result :The study showed that of the 90 patients who were included in the study had age range from 24yrs. to a maximum of 85 yrs. with a mean age of 51.5 years with (±14 SD).77 (85.6% presented with hoarseness of voice and Among those 34 cases for which risk factorswere specified 23 (67.6%) had cigarette smoking as risk factor while 12 (35.3%) had alcohol as risk factor.Out of the 79 cases with laryngeal sub sites described, 38 (48.1%) were transglottic, 27 (34.2%)glottic and 12 (15.2%) were supraglottic.46 (51.1%) patients had extra laryngeal spread, 18 (20%) had no extra laryngeal spread, and for26 (28.9%) cases it was not specified.Laryngoscopic cases of glottic location correlates with 46.2% of imagingcases of glottis acancer with the rest 46.2% being transglottic and 7.7% being supraglotic on imaging.