Browsing by Author "Aga Fekaduh"

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    Survival Status and Predictors of Mortality among Neonates Admitted with Hyperbilirubinemia in Neonatal Intensive Care units of Public Hospitals in Addis Ababa, Ethiopia, 2023
    (Addis Ababa University, 2023) keto Terefe; Aga Fekaduh
    Background: Neonatal jaundice is a major cause of neonatal intensive care unit admission and isone of the leading causes of morbidity in neonate. However, little is known about the time to deathand its predictors among neonates with hyperbilirubinemia. Therefore, this study aimed to assesssurvival status and predictors of mortality among neonates admitted with hyperbilirubinemia inneonatal intensive care units of public hospitals in Addis Ababa. Methods: This retrospective cohort study was conducted in public hospitals in Addis Ababa,Ethiopia, and included 380 neonates admitted with hyperbilirubinemia from January 2021 toDecember 2022. The data was collected from patient cards using a simple random samplingmethod with a pretested checklist between March 16 and April 16, 2023. Data entry was performedusing Kobo toolbox, and analysis was conducted using SPSS version 26. Kaplan Meier analysiswas used to estimate the median survival time and cumulative probability of survival, while thelogrank test was used to compare survival curves among different predictor groups. Therelationship between independent and outcome variables was analyzed using the Cox proportionalhazard regression model, with statistical significance set at a p-value of <0.05 and a 95%confidence interval. Results: The overall incidence density of mortality was 18 per 1000 person-day observations (CI:13-25) with 1980 follow-up days. Several factors were identified as significant predictors ofmortality, including maternal age below 20 years (AHR = 18.2, 95% CI: 3.2–102.7), living in arural area (AHR = 4.16, 95% CI: 1.64-10.52), premature rupture of membranes (AHR = 3.49, 95%CI: 1.14-10.66), gestational age below 37 weeks (AHR = 7.3, 95% CI: 1.84-28.8), birth weightbelow 2500gm (AHR = 15.1, 95% CI: 3.85-59.5), requiring both phototherapy and exchange bloodtransfusions (AHR = 48.6, 95% CI: 7.30-323.4), and presence of sepsis (AHR = 3.03, 95% CI:1.17-7.9). Conclusion: The neonatal mortality among neonates admitted with hyperbilirubinemia in Addis Ababahospitals is high. This suggests that there is a room for improvement in order to meet the 2030 WHOtarget of 12 or less deaths per 1,000 live births. Therefore, special emphasis should be given forneonates who were born from mother whose age is <20 years and from rural settings, present withPROM and neonates with GA <37 weeks, Birth weight <2500gm and neonates with sepsis