Browsing by Author "Deyessa, Negussie(MD, MPH, PHD)"

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    Survival to recovery in children with severe acute malnutrition treated at outpatient therapeutic care program in Southern Ethiopia.
    (Addis Abeba University, 2013-06) Merid, Melkamu; Deyessa, Negussie(MD, MPH, PHD)
    Background: Community-based management of severe acute malnutrition has been widely rolled out and integrated to the existing health care system in Ethiopia. But there is a dearth of information concerning the survival to recovery of severely acutely malnourished children after rolling out of the program to a health post level in the country. Objectives: To examine survival to recovery in children with severe acute malnutrition treated at outpatient therapeutic care program in Southern Ethiopia. Method and materials: Institution based retrospective cohort study was conducted using a data available from Jan. 2011 to Jan. 2013 in twelve randomly selected health posts. A two population proportion formula was used to calculate a sample size of 374. Descriptive analysis was done using percentages for categorical data and mean/median for continuous variables. Chi-square was used to measure associations between categorical variables. The Mann-Whitney U test for the independent two samples test was used to compare the medians for non-normally distributed continuous variables. The outcome variable was time to recovery. The life table analysis and the Kaplan-Meier product limit were used to estimate the survival characteristics of the study subjects. And the log rank test was used to compare the survival curves. The Cox proportional-hazard regression model was used determine predictors of time to recovery. Result: A total of 348 patient cards were reviewed. The median time to recovery was 35 days and 49 days for children with kwashiorkor and marasmus respectively. It was significantly different (Log Rank=46.93, df=1 P<0.001). There was a 1.2% decrease in the likelihood of recovery for one month increase in age (AHR=0.988, (0.977, 0.999)). Children with marasmus were also 48% less likely to recover (AHR=0.517, 95% CI (0.386, 0.691)). Children who had a weight gain of >=3.21gm/Kg/d were 2.43 times (AHR=2.434, (1.828, 3.241)) more likely to recover. For a MUAC gain (mm/day) of one unit increase there was a 2.33 times (AHR=2.326, (1.373, 3.942)) increase in the likelihood of recovery. Conclusion: Being marasmic, age, weight and MUAC gain were identified as a predictor of recovery. Hence it needs special attention on counseling the care taker about the appropriate way of feeding the therapeutic diet to the sick child to improve weight and MUAC gain with due emphasis given to marasmic children.
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    Validity and reliability of Cancer Therapy Satisfaction Questionaire (CTSQ) among cancer out patients in Tikur Anebssa Specialized hospital, Addis Ababa, Ethiopia
    (Addis Ababa University, 2019-10) Shimelis, Hiwot; Deyessa, Negussie(MD, MPH, PHD); Abreha, Aynalem( MD, oncologist ); Ayele, Wondimu(MSC, PHD Can.)
    Background- Cancer is becoming the most challenging issue in adult and geriatrics and intervention on patient therapy satisfaction is not commonly seen. The burden of cancer in morbidity and mortality is increasing through time .Cancer Therapy Satisfaction Questionnaire is the most widely used tool used to assess the satisfaction of cancer therapy in cancer patient. It is used to classify satisfaction for cancer patient as well satisfied or no satisfied. To improve quality of life different type cancer therapy has been given for the patients this can be measured through cancer therapy tools and tools in our context not validated so far. Objective- To test the reliability and validity of Cancer Therapy Satisfaction Questionnaire and to assess its relation with quality of life (QOL), among cancer patient in Tikur Anbessa Specialized Hospital Addis Ababa, Ethiopia. Method- Facility based cross sectional study was conducted from August to September 2019 among cancer patients in Black lion Specialized Hospital, Addis Ababa Ethiopia. A total of 288 cancer patients were selected using a Stratified random sampling technique. Cancer Therapy Satisfaction Questionnaire and one other (health-related) QOL questionnaire was administered among 288 randomly selected cancer patients. CTSQ has 3 domains and each domain has different number of Items. The reliability and validity of each Items of CTSQ were evaluated against the full Item of CTSQ. Accuracy, sensitivity, specificity and cut off point were evaluated to determine validity of CTSQ. The reliability also assessed using cronbaches αcoefficient. Criterion-related validity of the CTSQ was evaluated computing the correlation between total CTSQ score and total score of QOL-BREF. Result: The mean age (±SD) of the participants was 45.7±7.3 years. About 225(78%) females and 63(21%) males participated in the study. Cronbaches α value of full CTSQ tool was found 0.95.The overall accuracy of CTSQ was 0.89(95 % CI, 0.82%-0.96%), p< 0.001). The sensitivity and specificity of CTSQ using established cut of point was 92.3% and 83.6% respectively. The overall cancer therapy satisfaction was found to be 80.6%. Conclusion: CTSQ was valid and reliable to identify cancer therapy satisfaction among cancer patient and also CTSQ was positively correlate with QOL-BREF .CTSQ can be applied to measure cancer therapy in the Ethiopian contex