Zerihun, Dr. AdemeEshete, Gezahegn2021-10-082023-11-302021-10-082023-11-302006-06http://etd.aau.edu.et/handle/123456789/28082Contagious caprinc pleuro pneumo nia (Cepp) is a re s piratory disease of goms caused b) Mycoplasma ClIprico/1I111 subspecies capripne lll1lollioe (MccP). A Partic ipato ry Rural Appraisa l (PRA ) technique and IWO stage stratified cross secti o nal sero logical s urve y was conducted on ce pp fro m October 2005 to April 2006 in Afar pas torali st areas 10 determine the overall scropreva len ce of the disease and assess the impact o f communi!) animal health workers (CA HWs) on the di sease occ urrence. The s tud y po pulati on was stratified int o two based on differences in vClcri nar) service prov id ers in th e areas. A total of 1.183 sera samples ( 1.1 58 goats and 2S sheep) were tested usi ng complement fixation test (CFT) and com petiti ve enzyme linked immunosorbenl assay (cELl SA) tests. and 40 informant groups (on average 12 persons per grou p) \\ere in tervie\\cd. Results of the participator) disease assessment showed that among th e li\ cstocl.. 0 \\ ned. goats are thei r second preferences next to camel because of their comparative advantages espe c ia ll ) th ey are drought resista nt and have shan period of reproduction interval. The herders also id en tifi ed that CC PP \\as one of most comlllon di seases o f goals next to pa5. teurel losis and other stress associated diseases. causing high morbid i! ) and 1l10na lit). Out of 1.183 sera samples tested. 344 (29.08%) were se ropos it ive for MccP anti gen lI s ing CFT \e 5.1 and 19 . 19 % in the cE ll SA . In both CFT and cELlSA tests. univariate and multivariate anal~ sis of cpidellliologicall~ assumed ri sk fact ors showed that prevalence of CCPI' is hi gh ly assoc iated \\ ith the veterinary service provision through CA HW s. The serapositi\ ity \\as higher (36.78%.) in areas \\ here CA HW s are absent than CA HWs int e rve ntion a re as (21.42%). The seropre\alcllces ob<.;crved be tween these t\\O areas \\ere highl) significant (p < 0.001) using th e CFT t e~1. Th ere \\as also a significant difference (p < 0.00 I) bel ween non-CAHW s and CA II \\'s inlcn enlion areas usi ng cELlSA test with a mean seroprevalence of23.90% and 14.50%. re s pe eti\el). The agrecmem bel\\ cen the two tests was sligh t ( Kappa = 0.036) \' ith 64.24% concordance. Both tests could be used complim entari ly. x From the study it could be concluded tha t CCPP exists in its sub clinicalle\el in goats and its prevalence was lower in areas where the re is additional animal health service through NGOs supported CA HWs. Th is study has sho\\n thai CCPP is \\ ide I) distributed in Afar Regi o n. The indigenous kno\\Jedge of pastoralists is highl) appreciated \\hich act as a bridge and basis for an active disease search and inve stiga ti on and so it eQuid be used complementaril) \\ ith the com entional one in the prevention and control o f li\estock diseasesen: CCpp, participator) epidemiolog). CAHWs, seroprc\al ence. goats. AfaThesis