Boka,Abdissa(Ass. Prof.),Tesfayes,Tewodros(Ass. Prof.)Deressa,Melat2024-04-232024-04-232023https://etd.aau.edu.et/handle/123456789/2828Background Hand hygiene is the act of cleaning hands with water and soap and/or alcohol- based hand sanitizers to eliminate microbes. Practicing better hand hygiene decreases the spread of illnesses linked to healthcare, it is always been considered one pillar of infection control. According to the world health organization 2019 healthcare-associated infection fact sheet report, in underdeveloped nations, neonates are at a significant risk of getting infections related to healthcare. Objective: The aim of the study is to evaluate hand hygiene practice and associated factors among health care workers working in NICU of selected public hospitals, Addis Ababa, Ethiopia, 2022. Methods: A facility-based cross-sectional study design was done from March 21, 2022 - June 30, 2022. All health care workers working in selected hospital’s NICU in a study period included in the study. Data was collected through a self-administered questionnaire adapted from world health organization and a previous similar study. Data were entered into Epi data version 3.1 and transferred to a statistical package for social science SPSS version 20 for data analysis. Bivariate logistic regression and multivariate logistic regression used to see the association factors with dependent variable. Statistical significance was assured by a p-value <0.05. Figures, tables, and graphs were used to display the results. Results: The research included 140 healthcare personnel, with a 100% response rate. 31.4% of them practiced proper hand hygiene. Receiving training, accessibility of soap and water, personal towel/tissue, and poster near hand washing sink were found significantly associated with the dependent variable. Conclusion: There is a significant gap in hand hygiene practice by NICU health care workers in Addis Ababa. Possible explanations for this gap include a shortage of training, lack of soap and water, lack of personal towel and poster. As a result offer training as well as outfit the workplace with resources that promote good hand hygiene.en-USHand Hygiene, PracticeThesis