Ahmed AbdellaSalih HassenSamson Kehali2026-04-032026-04-032025https://etd.aau.edu.et/handle/123456789/8027Prelabour rupture of membranes refers to the loss of integrity of fetal membranes prior to the onset of clinically apparent labour contractions. The major issue in managing a woman with PROM at term is whether to follow her expectantly or proceed for delivery. Among the factors to consider are possibility of failed induction, caesarean delivery, length of labour, cost, length of hospitalization and risk of maternal and neonatal complications. Objective: the objective of the study is to assess the success rate, maternal and perinatal outcomes, and factors affecting of induction for prelabour rupture of membrane in the three teaching Hospitals of Addis Ababa University. Methods: Facility based cross-sectional study was employed in the three affiliate teaching hospitals of Addis Ababa University. The study subjects were recruited sequentially until the calculated sample size of 374 is achieved. The data were collected by interview & reviewing participants‘ clinical records. The data were entered, clearing and analysis by SPSS version 25. Logistic regression analyses were employed to identify factors associated with the outcome variable. Using 95% CI, variables with a p-value <0.05 were identified as statistically significant factors. Result: Sixty seven percent (n= 250) of 374 participants with PROM had a successful induction of labor. Multiparity (Odd‘s ratio= 14.0, 95% CI: 3.78, 52.16), term PROM (Odd‘s ratio= 4.9, 95% CI: 1.04, 23.29), and absence of intrapartum complications (Odd‘s ratio= 15.0, 95% CI: 13.37, 65.13) were significantly associated with higher odds of successful induction. Maternal complications occurred in 6.4% (n= 24) of participants, mainly postpartum hemorrhage (n= 21, 5.6%) and surgical site infection (n= 3, 0.8%). Poor perinatal outcomes were observed in 18% (n= 67) of neonates, with 16% (n= 59) requiring NICU admission and a neonatal mortality of 2.7% (n= 10). Multiparous women had a better perinatal outcomes (Odd‘s ratio= 0.39, 95% CI: 0.17, 0.92), while hypertensive disorders (Odd‘s ratio= 13.4, 95% CI: 1.03, 44.92) and non-spontaneous deliveries, OVD (Odd‘s ratio= 28.2, 95% CI: 2.73, 91.31) and CS (Odd‘s ratio= 6.2, 95% CI: 2.58, 14.96) significantly increased the risk. Conclusion and recommendation: The success of induction was good, and is comparable to the findings of studies done in other centers. Multiparity, term PROM, and absence of intrapartum complications were associated with successful induction. Strengthen antenatal risk assessment to identify women at higher risk for poor outcomes; those with hypertensive disorders and primigravidity is important to improve the outcome.enInductionPrelabour Rupture of MembranesAAUThesis