Dr. Messele, BruckDr. Beedemariam, GebremedhinHadush, Fikadu2020-11-242023-11-062020-11-242023-11-062020-09http://etd.aau.edu.et/handle/123456789/23482Patients’ belief and knowledge about medicine and diabetes disease on medication adherence and glycemic control among T2DM patients at Alamata General Hospital, Northern Ethiopia Fikadu Hadush Addis Ababa University, 2020 Introduction: About 45% of T2DM patients had poor glycemic control and 45.2% of patients had poor medication adherence, those could be affected by diabetic disease knowledge, belief about medicines, socio-demographic and clinical determinants. However, there is dearth of data in the Northern part of Ethiopia with regards to glycemic control status and medication adherence. Objective: To assess influence of patient’s belief and knowledge about medicine and diabetes disease on medication adherence and glycemic control among T2DM patients at Alamata General Hospital, Northern Ethiopia. Methods: A cross sectional study design was conducted among T2DM patients at Alamata General Hospital from September to December, 2019. Data was collected through medical chart review and face-to-face interview of patients using structured questionnaires. Descriptive statistics and multivariable logistic regression were employed to identify predictors of medication adherence and glycemic control. Results: A total of 305 T2DM patients were included in the study where a little over half were male and had no formal education with mean age of 56.5 ± 12.4 years. Of these, 44.6% of the patients had poor medication adherence, 75.7 % had poor glycemic control and 84.3 % of patients had poor diabetes disease knowledge. Patients who had T2DM disease for more than 10 years (AOR=3.87; 95%CI (1.48-10.07)), high concern belief of anti-diabetic drugs (AOR= 20.63, 95%CI (5.15-82.61) and poor diabetes disease knowledge (AOR=4.54; 95%CI (1.53- 13.46)) were determinants of poor medication adherence. Conversely, having high necessity belief of anti-diabetic drugs (AOR=0.21; 95%CI (0.11-0.40) was inversely associated with poor medication adherence. Meanwhile, being high school student (AOR= 5.54; 95%CI (1.11– 27.60)), TVET/Diploma holder (AOR=9.27; 95%CI (1.98–43.36)) and poor diabetes disease knowledge (AOR=4.34; 95%CI (1.74-10.81)) were predictors of poor glycemic control level. Whereas, patients who were taking combination of oral hypoglycemic agents and insulin (AOR=0.33; 95%CI (0.15- 0.71)) and those who had house hold monthly income more than or equal to 3925 ETB (AOR=0.18; 95%CI (0.06-0.48)) were inversely associated with poor glycemic control. Conclusions: About half of T2DM patients had poor medication adherence and three-fourths of the patients had poor glycemic control. Therefore, regular diabetes health education should be given to enhance their awareness about their disease and medicine use.en-USMedication adherence, T2DM, glycemic control, belief about medicines and diabetes disease knowledge.Thesis