Dr. Argaw, Rahel(Md, Pediatric Pulmonology And Critical Care).Tuli, Wagari(Aauchs, Msc, Emccn, Lecturer).Dr.moges, Ayalew(Md,Pediatric Neurology)Habtamu, Asaminew2020-11-122023-11-052020-11-122023-11-052020-01http://etd.aau.edu.et/handle/123456789/23217background: - seizure is a transient occurrence of signs and symptoms resulting from abnormal excessive neuronal activity in the brain. It is an important cause for hospital admissions in children from developing countries. it accounts for about 1% of all emergency department visits, and about 2% of visits to children's hospital emergency department visits. It is a major factor for neurological and cognitive impairment in children living in sub-saharan africa. Limited studies have been conducted in ethiopia relating to the prevalence and associative factors of seizures in children. Objective: - This study aims to assess the magnitude of seizure and its’ associated factors among 1 month -12 years of age children admitted in tikur anbessa specialized hospital(tash), at the pediatric emergency unit from december 2016- december 2019. Result: - Medical records review was done for 256 children with a 96% response rate. The prevalence of seizure was 4.52 %( 45/1000 people) . 155( 60.5%) were males and with a male to female ratio of (1.5:1). the mean age of patients was 3.7 years (with standard devation 2.8). The mean age for onset of a seizure in males and females was 1.3(sd 1.1-1.5 at 95% ci) and 2.0(sd1.6-2.5 at 95% ci) respectively. on logistic regression, fever (or 1.85,p=0.01), newborn distress (or 2.31,p=0.01), hypoxia brain injury (or 2.43,p=0.00), and home delivery (or 2.8,0.04) were found to be significant predictors seizure.head trauma was 1.3 times more likely to had an earlier onset of the pediatric seizure, (aor: 1.3,p=0.00) , birth asphyxia, (aor: 2.3,p=0.00) hypoxic brain ischemia, (aor, 2.2,p=0.02)developmental delay, (aor, 2.5,p=0.01),fever, (aor, 1.2,p=0.01),male (aor, 2.7,p=0.01) were significantly associated with pediatric seizure early onset at p<0.05 with 95% ci. Conclusion:-:-this study has identified a considerable burden of seizure in younger children in this hospital. fever, perinatal insults and place of delivery were significantly associated with pediatric seizure .underlying the need to advocate the need of proper management of pregnancy and delivery Recommendation; -Health professional at different levels and institution should work to reduce the occurrence of childbirth asphyxia that commonly show most associations with pediatric seizure. health facilities better to give health education and health promotion to improve, the awareness on the risk factors of a seizure.en-USSeizure, pediatric emergency, tikur anbessa specialized hospital.Thesis