Mekonnen,Hussen(PhD)Wondimagegnehu,Abigiya(PhD candidate)Nadew,Tigle2025-08-132025-08-132024-06https://etd.aau.edu.et/handle/123456789/6611Background: Chronic kidney disease patients on hemodialysis have an increased risk of infection due to the nature of the disease and the type of treatment they receive. In many developing countries including Ethiopia, there is low level of compliance of infection prevention practice between medical professionals, despite the rise of highly contagious illnesses. Effective interventions can be developed by critically assessing the elements that contribute to this problem. Objective: To assess infection prevention compliance and associated factors among nurses working at dialysis units for chronic kidney disease patients in Addis Ababa. Methods: A facility-based cross-sectional study was carried out among nurses working at dialysis units for chronic kidney disease patients in Addis Ababa from Jan-March 2024. A total of 251 nurses were included. A structured self-administered questionnaire which has eight components and a checklist were used for data collection. Descriptive statistics and correlation estimates were used. For regression analysis, the study applies Principal Component Analysis to generate an index. Finally, logistic regression was done and adjusted odds ratio (AOR) with a 95% confidence interval was estimated in the final model. P-values of below 0.05 were regarded as significantly associated variables. Results: The result showed that 105 nurses 45.66% were non compliant to infection prevention and control practices. The multivariable logistic regression result indicates, monthly salary10,000.00-20,000.00) [(AOR:3.23 ,95%CI (1.20-8.70)], nurses who had duty [(AOR: 0.48 ,95%CI (0.25-0.93)], and work environment factor [(AOR: 6.57 ,95%CI (3.38-12.78)] were predictors of infection prevention compliance. Conclusion and recommendation: Infection prevention compliance was not sufficiently practiced among dialysis unit nurses. Monthly salary, frequency of duty and work environment factors were factors associated with infection prevention compliance. Thus, intervention should focus on encouraging nurses by giving competitive benefit through salary increment, decreasing workload and creating good work environmental factors by ensuring sufficient and sustainable resources.en-USInfection preventioncompliancenursesdialysis unitsAddis AbabaEthiopiaThesis