Dr.Gemechu, Endalew (Ass. Prof)Getahun, Negalign(MSC)Tolessa, Lidia2020-12-142023-11-052020-12-142023-11-052020-06http://etd.aau.edu.et/handle/123456789/24047Introduction: Breast cancer is the leading cause of cancer- related death in women worldwide. In Ethiopia its incidence is rising, causing high rates of morbidity and mortality currently in the country. There is a variation in the prevalence of underlying risk factors among different countries. However, study that examines the local risk factors of breast cancer among women is limited in Ethiopia. Objective: To assess risk factors of breast cancer among patients attending Tikur Anbessa Specialized Hospital and St. Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia, 2020. Methods: Institutional-based case-control study was conducted with a sample of 272 women (136 cases and 136 controls). Cases and controls were selected by a systematic random sampling technique. Data was collected by interviewer administered questionnaire and the collected data was cleaned for incompleteness using Epi dataversion 4.6. Data analysis was carried out using SPSS version 25. Descriptive statistics wereemployed and bivariate and multivariate analysis using Odds ratio (OR) were utilized to evaluate the association between dependent and independent variables. A p-value of less than 0.05 was considered as a level of significance for associations. Results: In this study, a total of 272 participants with 136 cases and equal number of controls were participated. The mean (+SD) age of the participants was 42.7(±11.3) and 40.7(±14.6) for the cases and controls respectively. Increased risk of breast cancer was associated with early onset of menarche (AOR=7.9; 95% CI (1.959-31.905)) and use of packed food or drinks (AOR=4.4; 95% CI (1.481-13.218)). Living in urban areas (AOR=0.1; 95% CI (0.016-0.712)) and increased parity (AOR=0.750; 95% CI 0.567-0.992) were associated with reduced risk of breast cancer. Conclusion and recommendation: According to the finding of this study, place of residence, age at menarche, parity and use of packed food or drinks were associated with breast cancer. Therefore, attention should be given on specific risk factors, to reduce the increasing burden of the disease in our country.en-USBreast cancer ,PatientsThesis