Mamo Hassen (PhD)Lule Abe2020-11-192023-11-092020-11-192023-11-092019-08-08http://etd.aau.edu.et/handle/123456789/23397Malaria is one of the major public health problems worldwide. In Ethiopia there is significant decline in disease burden, however the overall trend of malaria prevalence is not studied or not documented in different locality. The aim of this study was to analyses the past eight years and current status of malaria prevalence in Kuergang town, Nuer zone, Gamblla. Retrospective laboratory record review was conducted in Kuergang health center (2011 to 2018), which was carefully reviewed from September, to December. In this study the prospective data from September 2018 to February 2019 was also analyzed. Patients visiting the health center between September 2018 and February 2019 were successively recruited .Blood samples were drawn and examined by following standard procedures. A total of 10850 examined blood films were prepared and examined from malaria suspected patients at Kuergang health center. Of the examined blood films 5223(48.1%) were confirmed as RDT positive. The trend of malaria prevalence in the study seems slightly fluctuated. Malaria cases were higher in males 2963(56.7%) than 2260(43.3%) females. P. falciparum and p. vivax were accounted for 3804(72.8%) and 925(17.7%) respectively. From the total positive cases 494(9.5%) were mixed (P-falciparum and P. vaivax ).In the prospective study a total of 2808 suspected cases of malaria were reported at Kuergang health center. Of this 924(33.0%) were RDT positive. Among these positive cases 526 (57.0%) and 398(43.0%) were males and females respectively. Higher number of malaria cases was observed in >18 age category. There was higher percentage 750 (81.1%) of p. falciparum infection than p. vivax 106 (11.5%) and mixed 68(7.4%) cases. In prospective study there was peak malaria transmission period in September 201(58.9%) and October 249(39.7%).From June to September malaria prevalence was high in the past eight years. This study showed that more males were infected with malaria in retrospective study. P. falciparum was the dominant parasite in both retrospective and prospective study. Seasonal variation should be well recognized with special focus given to annual peak seasons (months), to prevent high malaria transmission.enPrevalenceKuergangProspectiveRetrospectiveMalariaP. FalciparumP.VivaxThesis