Gemechu Endalew(PHD)Daba Workinesh(BSc)Gedamu Samuel2020-06-032023-11-062020-06-032023-11-062019-07http://etd.aau.edu.et/handle/123456789/21415Background: Congenital anomalies, affect millions of babies worldwide with a prevalence of 3% and it is estimated that, globally, 303,000 newborns die within the first 4 weeks of life due to congenital anomalies. In Ethiopia, there are a number of babies are born with congenital anomalies; however, a few studies have been studied regarding the prevalence and risk factors for the anomalies. Objective: The main objective of this study was to assess the prevalence of congenital anomalies and associated factors among newborns in Bishoftu general hospital,Oromia, Ethiopia. Methods: descriptive retrospective crossectional study was employed. The data entry and analysis was conducted by using SPSS version 24. Categorical variables were summarized as proportions and were compared using Pearson’s Chi square test, Crude (unadjusted) and adjusted odds ratios were calculated to quantify the strength of association between the factors and congenital anomalies. The 95% confidence intervals were determined and the factors with a p-value of less than 0.05 were considered to have a significant association with congenital anomalies. Result: Out of 2218 live births 23 newborns were diagnosed with congenital malformations, making the prevalence rate of 1% per 100 live births. The most common prevalent types of congenital anomaly were anencephaly (30.4%).Maternal age above 35(AOR =6.5, 95%CI = (2.4-18), P value= 0.001),birth order above 3(AOR=8.4; 95%CI=3.420.7; Pvalue=0.001),birtweight less than 2.5(AOR=0.3;95%CI=0.1-0.9),P value=0.037)and singleton pregnancy(AOR =6.4;95%CI =2-18.9,P value =0.001) had a significant association with the occurrence of congenital anomalies, whereas maternal use folic acid during pregnancy(AOR=0.036; 95% CI =.0.008-0.15;Pvalue=0.001) had a protective effect against congenital anomalies. Conclusion and recommendation: Congenital anomaly is common and accounts for 1 %( 10/1000 live births) in Bishoftu general hospital and anencephaly is the most prevalent type followed by hydrocephalus and spinal bifida. Large community-based studies in different geographical, environmental and socio-economic settings should be conducted in Ethiopia to determine the prevalence of congenital anomalies and their associated factors.en-USCongenital anomalies, prevalence, newborns, Bishoftu general hospital.Thesis