Bitew, Adane (Associate Professor)Abebaw, Yeshiwork2018-07-032023-11-062018-07-032023-11-062016-10http://etd.aau.edu.et/handle/123456789/6048Background: Bacterial vaginosis and vulvovaginal candidiasis are major health problems associated with gynecologic complications Objective: To determine the prevalence bacterial vaginosis and vulovvaginal candidiasis among women complaining genital tract infection at SPHMMC and FGAEMC Addis Ababa, Ethiopia. Methods: A health facility based cross sectional study was conducted from February,2016 to July, 2016. Demographic variables were collected using a structured questionnaire. Two vaginal swab specimens were collected from each participant. For diagnosis of bacterial vaginosis ,gram stain Nugent score was used. All fungal and bacterial pathogens were isolated and characterized by employing conventional techniques. Antimicrobial susceptibility profile of bacterial isolates was Performed using disc diffusion technique as per the standard Kirby-Bauer method. The results were analyzed using SPSS version 20. Result: The overall vaginal infection was 70% .The overall prevalence of bacterial vagnosis was 102(48.6%).Bacterial vaginosis was statistically significant associated with odor (p=0.007), frequency vaginal bathing (p=0.045) and frequency of changing of pants (p=0.01). The overall prevalence of vulvovaginal candiasis was 87(41.4%).Vulvovaginal candidiasis was statistically significantly associated with illiterate patients (p=0.021), number of life time male sex partner (p=0.037), number of sex partner in the last 12 months (p=0.001) and with previous bacterial vaginosis (p= 0.004). A total 151 bacterial isolates were recovered, of which 105(69.5%) of the isolates were gram negative and 46 (30.5%) isolates were gram positive bacteria. The overall drug resistance rates of gram negative bacterial isolates ranged from 14.3% to Amikacin 77.3% to Tetracycline. The overall drug resistance rates of gram positive bacterial isolates ranged from 0% to vancomycin and 67.4% to penicillin. Conclusion and recommendation: Both bacterial vaginosis and vulvovaginal candidiasis was high and hence many such types of studies are recommended to be conducted across the country. Keywords: Bacterial Vaginosis and Fungi isolateenBacterial Vaginosis and Fungi isolateThesis