Alem miritBinyam Mebrat2025-08-122025-08-122024-03-13https://etd.aau.edu.et/handle/123456789/6492Tuberculosis is a major global public health concern and the emergence of drug- resistant (DR)-TB has been a major challenge to the control of the disease, especially in developing countries, including Ethiopia. Despite availability of appropriate diagnostic tools for Mycobacterium tuberculosis drug susceptibility testing, accessibility and timely diagnosis of DR-TB in resource-constrained settings, such as Ethiopia, is often a challenge. The first- generation color plate assay (1G) is ideally suited for low resource settings due to low cost, minimal technical expertise needed, and rapid provision of DST results.en-US1G testcolor plate testindirect proportional DST MethodMultidrug-resistant tuberculosisPre-XDR TuberculosisTuberculosisThesis