Mitiku,Shiferaw(PhD)Endale, Betelhem2024-04-232024-04-232023https://etd.aau.edu.et/handle/123456789/2807The COVID-19 pandemic is causing unprecedented or extraordinary human and economic costs in all countries and societies across the world. After the WHO declared COVID-19 to be an international public health emergency vaccines were manufactured within one year. The Purpose of the study was to assess COVID-19 vaccine cold chain practice, challenges of cold chain management practices and vaccine utilization in selected government health facilities under the Addis Ababa Health Bureau. Both quantitative and qualitative research approach were employed. The population of the study was EPI focal persons who work in health facilities under 47 which accounts (44 health centers and 3 hospitals) and questionnaires were used to collect data and secured 95% response rate. Challenges of cold chain practice and utilization were filled using the five point likert scale and questionnaire was coded and analyzed using SPSS-V-20.Descriptive statistics mean were under taken regarding on cold chain capacity, stock management and vaccine storage temperature practiced slightly but regarding to cold chain equipment highly practiced. Furthermore, cold chain management challenges are influential in insufficient cold chain capacity, lack of latest technology or standard vaccine fridge, inadequate temperature monitoring and maintenance system, knowledge gap of health workers on cold chain practice as dependent variable. For COVID-19 vaccines cold chain management practice: AACAHB, Sub city offices and other stakeholders should improve practice in storage capacity should be assessed and assign experienced cold chain equipment maintenance technicians at the facility level.COVID-19 vaccines require special storage temperature monitoring and stock management by using introduction of temperature monitoring and by identify and address logistical issues such as the distribution of adequate storage equipment and give training should be provided periodically to improve stock management and minimize wastage of vaccine.en-USChallenges cold chain management practiceCOVID-19 vaccine practiceThesis