Gesso,Ashenafi Seifu (MSc)Delile, Siryet Tesfaye(MSc)Kolbaye,Eshetu Tomas2025-08-132025-08-132024-05https://etd.aau.edu.et/handle/123456789/6599Background- When used for cesarean sections, both spinal anesthesia and general anesthesia have certain advantages as well as disadvantages. Because of time limitations, general anesthesia is still preferred for category-1 cesarean sections despite its drawbacks. Hence, this study aims to compare of general anesthesia versus spinal anesthesia on new-born and maternal outcomes in clients undergoing category-1 cesarean sections. Objective: To compare the effect of general anesthesia versus spinal anesthesia on new born and maternal outcomes among category-1 caesarean sections clients from February 1/2024 to April 30/2024. Method: Institutional based prospective cohort study was conducted at Ghandi memorial hospital Addis Ababa Ethiopia. 152 clients who had emergency category-1 cesarean sections included based on inclusion criteria. Clients were subdivided into 2 groups (General anesthesia 91 and Spinal anesthesia 61). A well-structured questionnaire was used to collect the data. New born and maternal outcome were compared between the study groups. Version 26 of SPSS was used for the statistical analysis. The collected data were entered into SPSS software version 26.0 for analysis. The Chi- square/Fischer exact test was used to compare categorical data and an independent sample t test or Mann–Whitney U test was used to compare continuous data as appropriate. The p- value of 0.05 was taken as a cut-off point to determine statistical significance. Result: A total of 152 who underwent category-1 cesarean section clients were enrolled in this study and were included for analysis. General anesthesia group (91) and spinal anesthesia group (61). The general anesthesia group's 1- and 5-minute Apgar scores were significantly lower than those of the spinal anesthesia group, with median value of 7(7-8) vs 8(7-8), p < 0.001 at 1 min and 8(8-8) vs 9(8-9), p< 0.001 at 5 min respectively. Conclusion and recommendation: In this study, general anesthesia for category 1 CS was associated with a higher risk of unfavourable neonatal outcomes. Our recommendation is to give preference to spinal anesthesia over general anesthesia.en-USCategory 1 caesarean sectiongeneral anaesthesiaspinal anaesthesianew born outcomes and maternal outcomes.Thesis