Girma, Mesfin( MD,Assistant professor)Damene, Tsigereda(MD)2018-10-242023-11-052018-10-242023-11-052017-11http://etd.aau.edu.et/handle/123456789/13150Background Laryngospasm is usually easily detected and managed, but may present atypically and/or be precipitated by factors which are not immediately recognized. If poorly managed, it has the potential to cause morbidity such as severe hypoxemia, bradycardia, pulmonary aspiration, and post-obstructive pulmonary edema and end up with mortality if not treated. Objectives To assess the magnitude and associated risk factors of perioperative pediatrics laryngospasm during elective general surgery under general anesthesia. Methods Hospital based cross sectional study was conducted on elective pediatrics patients who underwent elective general surgery in Tikur Anebessa University Teaching Hospital from Aug 1, 2017 to Nov1, 2017. Result: From the 68 (21.8%) laryngospasm events identified as cases, during induction 38(12.2%), maintenance 14(4.5%) and emergence 16(5.1%). About 40(12.8) % were precipitated by direct airway stimulations and 19(6.1%) by light plain of anesthesia. Desaturation occurred in 39 (12.4%) of cases, bradycardia in 16 (5.1%), pulmonary aspiration 11(3.5) and negative pressure pulmonary edema 2 (0.6) of case. There is statistical association between status of the providers with the incident of laryngospasm (p-value 0.025). 39 (12.4%) of cases were managed by administration of 100% oxygen with positive pressure or continuous positive airway pressure, deepen anesthesia 17(5.4%), removal of stimuli 11(3.5%) and only 1 (0.3%) case was treated with intravenous succinylcholine with absence of response for other management options. There was no statistical significance with type of airway management devices used with the occurrence of laryngospasm. Conclusions: laryngospasm is mainly associated with airway manipulation and light anesthesia.en-USperioperative, Pediatrics, laryngospasm, elective general surgery, general anesthesiaThesis